Showing papers by "Ivone Antônia de Souza published in 2019"

Evaluation of cytotoxicity and wound healing activity of Avicennia schaueriana in cream.

Abstract: Avicennia schaueriana is found in Brazilian mangrove coast The cytotoxicity in vitro of the Aqueous Extract of Leaves of Avicennia schaueriana (AELAs) and the healing activity of the plant in cream on mice skin wounds were evaluated in this study The cytotoxic evaluation was performed on Vero cells The healing activity was evaluated on mice treated during 5, 10 and 15 days with cream at 5%, solution of sodium chloride at 09% and dexpanthenol in cream at 5% The extract did not show cytotoxicity, but showed mitogenic activity (100μg/ml) In morphometric analysis, the percentage of wound contraction after 10 days was higher in dexpanthenol group (9341%) In 15 days, the lowest percentage of contraction was observed in the dexpanthenol group (9441%) and the highest in the AELAs cream group (9850%) In histomorphometry the dexpanthenol showed the lowest length of re-epithelialization in 10 days In 15 days, the AELAs cream group showed 100% of re-epithelialization The number of fibroblasts found in AELAs cream group was higher than the saline solution in 10 days In 15 days, AELAs cream group maintained a higher amount of fibroblasts when compared to the others A schaueriana did not show cytotoxicity Furthermore, topical application of AELAs cream decreased the wound area, stimulated the re-epithelialization and increased the number of fibroblasts The species A schaueriana could become a topical treatment in tissue repair process

CYTOTOXICITY ASSESSMENT AND ANTIMICROBIAL ACTION OF Caulerpa taxifolia (M. Vahl) C.

Abstract: This study aims to determine the LC50 for Artemia salina Leach and perform a microbial screening two C. taxifolia extracts. In these biological assays have been used larvae of A. salina Leach ob-tained from the incubation of about 20 mg of A. salina cysts, under artificial light for 48 hours. Where groups of 10 metanauplius were exposed to different concentrations (50 mg / mL to 1000 ug / ml) of methanol extract and hydroalcoholic C. taxifolia . The antimicrobial activity of extracts of C. taxifolia was evaluated by diffusion method in paper disc. The percentage mortality deter-mined after 24 hours of contact. Through the data was calculated LC50. Behavioral analysis of Artemia salina Leach showed a decrease in handling compared to those observed in the control groups. The microbial activity of the extracts were evaluated by measuring the halo of inhibition for two species of gram-positive and two gram-negative bacteria. The extracts showed signifi-cant results for S. aureus and S. spp. This study demonstrates that C. taxifolia has a high cyto-toxicity suggested that its use in cell culture as a molluscicide and can be used in the production of production of antimicrobial drugs.

Rizophora mangle e ácido tânico: uma associação em creme para o tratamento de feridas

Abstract: MARINHO, Anneliese Goncalves Costa, tambem e conhecida em citacoes bibliograficas por: COSTA, Anneliese Goncalves