J
J C Louis
Researcher at Weizmann Institute of Science
Publications - 2
Citations - 130
J C Louis is an academic researcher from Weizmann Institute of Science. The author has contributed to research in topics: Protein kinase C & Brain ischemia. The author has an hindex of 2, co-authored 2 publications receiving 129 citations.
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Journal ArticleDOI
Protein kinase C alterations in the fetal rat brain after global ischemia.
TL;DR: Activation and possible deregulation of protein kinase C are proposed to represent an initial step in the pathophysiology of brain ischemia.
Journal ArticleDOI
Gangliosides prevent ischemia-induced down-regulation of protein kinase C in fetal rat brain.
TL;DR: PKC activity is translocation from a cytosolic to a membrane‐bound form in the fetal brain and down‐regulation of PKC is accompanied by an increase in a Ca2+‐phosphatidylserinc‐indepcndent kinase [protein kinase M (PKM)] activity, suggesting that PKC down‐ regulation and PKM activity elevation are intimately associated events and that both are regulated by GM1 ganglioside.