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J. de Graaff

Researcher at Academic Center for Dentistry Amsterdam

Publications -  138
Citations -  6021

J. de Graaff is an academic researcher from Academic Center for Dentistry Amsterdam. The author has contributed to research in topics: Bacteroides & Streptococcus mutans. The author has an hindex of 42, co-authored 138 publications receiving 5895 citations. Previous affiliations of J. de Graaff include VU University Amsterdam.

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Potential role of molecular mimicry between Helicobacter pylori lipopolysaccharide and host Lewis blood group antigens in autoimmunity.

TL;DR: It is reported that lipopolysaccharides of H. pylori express Lewis y, Lewis x, and H type I blood group structures similar to those commonly occurring in gastric mucosa, which indicates a direct pathogenic role for anti-Lewis antibodies in H. Pylori-associated type B gastritis.
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Lactoferrin is a lipid A-binding protein.

TL;DR: In vitro-binding studies have demonstrated that LF binds directly to isolated lipid A and intact LPS of clinically relevant serotypes of the species which most frequently cause bacteremia, as well as to Lipid A and L PS of mucosal pathogens (among others, Neisseria meningitides and Haemophilus influenzae).
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Bacteroides endodontalis and other black-pigmented Bacteroides species in odontogenic abscesses.

TL;DR: It was found that Bacteroides endodontalis, a newly described species of asaccharolytic black-pigmented Bactroides, was isolated almost exclusively from periapical abscesses of endodental origin.
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Microbiological and Clinical Results of Metronidazole Plus Amoxicillin Therapy in Actinobacillus actinomycetemcomitans-Associated Periodontitis*

TL;DR: It was concluded that mechanical periodontal treatment in combination with the metronidazole plus amoxicillin therapy is effective for subgingival suppression of A. actinomycetemcomitans in patients with severe periodontitis.
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Experimental gingivitis during pregnancy and post‐partum: clinical, endocrinological, and microbiological aspects

TL;DR: During pregnancy, more swelling, redness and bleeding on probing developed during experimental gingivitis than post-partum, whereas the amount of plaque was similar in both phases, which suggests that as a result of dental plaque accumulation, gingival inflammation develops superimposed on pregnancy-associated physiologic alterations.