TOPICAL REVIEW: Applications of magnetic nanoparticles in biomedicine

Following Sharpless' visionary characterization of several idealized reactions as click reactions, the materials science and synthetic chemistry communities have pursued numerous routes toward the identification and implementation of these click reactions. Herein, we review the radical-mediated thiol-ene reaction as one such click reaction. This reaction has all the desirable features of a click reaction, being highly efficient, simple to execute with no side products and proceeding rapidly to high yield. Further, the thiol-ene reaction is most frequently photoinitiated, particularly for photopolymerizations resulting in highly uniform polymer networks, promoting unique capabilities related to spatial and temporal control of the click reaction. The reaction mechanism and its implementation in various synthetic methodologies, biofunctionalization, surface and polymer modification, and polymerization are all reviewed.

Thiol–Ene Click Chemistry

https://cyberleninka.org/article/n/1018032.pdf

Polymer nanotechnology: Nanocomposites

The physical principles underlying some current biomedical applications of magnetic nanoparticles are reviewed. Starting from well-known basic concepts, and drawing on examples from biology and biomedicine, the relevant physics of magnetic materials and their responses to applied magnetic fields are surveyed. The way these properties are controlled and used is illustrated with reference to (i) magnetic separation of labelled cells and other biological entities; (ii) therapeutic drug, gene and radionuclide delivery; (iii) radio frequency methods for the catabolism of tumours via hyperthermia; and (iv) contrast enhancement agents for magnetic resonance imaging applications. Future prospects are also discussed.

https://iopscience.iop.org/article/10.1088/0022-3727/36/13/201/pdf

Applications of magnetic nanoparticles in biomedicine

http://wwwcourses.sens.buffalo.edu/ce435/Riess03.pdf

Micellization of block copolymers

Synthesis and applications of heterobifunctional poly(ethylene oxide) oligomers

Synthesis and crosslinking of partially disulfonated poly(arylene ether sulfone) random copolymers as candidates for chlorine resistant reverse osmosis membranes

Flame retardant novolac–bisphthalonitrile structural thermosets

Preparation de copolymeres trisequences polycaprolactone/PDMS et poly(ethyl-2 oxazoline)/PDMS par copolymerisation de la caprolactone et de l'oxazoline avec les oligomeres telecheliques PDMS comme comonomeres et amorceurs. Mise en evidence par DSC et TMA de leur structure biphasique. Utilisation des copolymeres PCL/PDMS comme additifs modificateurs de surface de polymeres (PET, PMMA, PVC, PU), les melanges obtenus presentant des proprietes de surface hydrophobes

Novel triblock siloxane copolymers: Synthesis, characterization, and their use as surface modifying additives

Novel block copolymers are provided, comprising poly(oxazoline) blocks and polysiloxane blocks. Novel polysiloxane intermediates for preparing such block copolymers are also provided which contain benzyl halide terminal groups. The block copolymers are useful as surface-modifying additives for base polymers.

J. S. Riffle

Papers

Synthesis and applications of heterobifunctional poly(ethylene oxide) oligomers

Synthesis and crosslinking of partially disulfonated poly(arylene ether sulfone) random copolymers as candidates for chlorine resistant reverse osmosis membranes

Flame retardant novolac–bisphthalonitrile structural thermosets

Novel triblock siloxane copolymers: Synthesis, characterization, and their use as surface modifying additives

Polysiloxane/poly(oxazoline) copolymers