J
Jacyln D Gavino
Researcher at Brigham and Women's Hospital
Publications - 2
Citations - 407
Jacyln D Gavino is an academic researcher from Brigham and Women's Hospital. The author has contributed to research in topics: Cancer & Cell signaling. The author has an hindex of 2, co-authored 2 publications receiving 381 citations.
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Targeting selectins and selectin ligands in inflammation and cancer
TL;DR: Antagonists that target cellular interactions with E-selectin and other members of the selectin family, including neutralizing monoclonal antibodies, competitive ligand inhibitors or metabolic carbohydrate mimetics, exemplify a growing arsenal of potentially effective therapeutics in controlling inflammation and the metastatic behavior of cancer.
Journal ArticleDOI
Analysis of glycosyltransferase expression in metastatic prostate cancer cells capable of rolling activity on microvascular endothelial (E)-selectin.
Steven R. Barthel,Jacyln D Gavino,Georg K. Wiese,Jennifer M Jaynes,Javed Siddiqui,Charles J. Dimitroff +5 more
TL;DR: The results implicate the importance of alpha1,3 FT3, FT6, and/or FT7 in sLe(X) and ESL synthesis on metastatic PCa cells and contrast the expression level of glycosyltransferases in ESL(+) MDA cells among other ESL(-) metastaticPCa cell lines.