Showing papers by "Jae Young Lim published in 2002"

Risk factors of cerebral palsy in preterm infants.

Abstract: Han TR, Bang MS, Lim JY, Yoon, BH, Kim IO: Risk factors of cerebral palsy in preterm infants. Am J Phys Med Rehabil 2002;81:297–303.ObjectiveTo investigate the outcome of preterm infants and to determine the most important risk factors in the development of cerebral palsy.DesignThe outcomes

Clinicopathologic Study of Generalized Pustular Psoriasis and Acute Generalized Exanthematous Pustulosis

Abstract: Background : Generalized sterile pustular eruption with fever which occurs in generalized pustular psoriasis(GPP) and acute generalized exanthematous pustulosis(AGEP) present a diagnostic and therapeutic problems. In Korea, there are a few studies of clinical and histopathologic reviews of these diseases, but long term follow-up and comparative clinicopathologic studies of these two diseases are not available. Objective : This study attempts to identify the differences of these two disease in the aspects of clinical, laboratory, and histopathologic findings. Methods : We evaluated the clinical features, laboratory and histopathologic findings in 41 patients with generalized pustular eruption who had visited Pusan National University hospital during the past 20 years and reviewed the literature. Results : 1. The ratio of patients with GPP(n=32) to ones with AGEP(n=9) was 3.6:1. 2. The mean age at diagnosis was 32.9(male) and 28.9(female) years in GPP, and 10.3 years(male) and 62.8 years(female) in AGEP. 3. The number of patients of GPP with previous personal history of psoriasis vulgaris were 15/32 (46.9%) and the number of ones with previous family history of psoriasis vulgaris were 2/32(6.3%). 4. There was no patient of AGEP with personal or familial history of psoriasis. 5. The number of patients with recent drug intake history were 4/32(12.9%) in GPP and 9/9(100%) in AGEP. And common drugs suspected to cause AGEP were antibiotics(4 cases) and analgesics(3 cases). 6. Associated systemic symptoms were fever(37.5%), arthralgia(18.8%), and itching(62.5%) in GPP, whereas 66.7%, 33.3%, and 55.6%, respectively in AGEP. 7. The mean duration of pustules was 32.9 days in GPP and 7.2 days in AGEP. 8. Reccurences of generalized pustular eruption were 46.9% in GPP and 0% in AGEP. 9. Laboratory findings revealed leukocytosis(34.4%), elevated erythrocyte sedimentation rate(28.1%), hypoalbuminamia(25.0%), and eosinophilia(6.3%) in GPP, whereas 77.8%, 55.6%, 33.3%, and 71.4%, respectively in AGEP. 10. On histological findings, we observed psoriasiform acanthosis(78.1%) and Monro's microabscess(12.5%) in the specimen of GPP in contrast to papillary dermal edema(66.7%) and perivascular eosinophils(44.4%) in AGEP. Conclusion : GPP and AGEP are disease sharing similar clinical, laboratory, and histologic features. We suggest that it is important to be aware of these distinctions for avoidance of unnecessary aggressive therapy indicated for GPP.

Two Cases of Kerion Celsi Caused by Trichophyton tonsurans

Abstract: We report two cases of kerion celsi caused by Trichophyton tonsurans. One is a 16-year-old male Judo-player in athletic high school and the other is a 7-year-old boy. Kerion celsi is a highly inflammatory, suppurative fungal infection of the scalp caused mainly by zoophilic dermatophytes transmitted from animals to man. The first case presented with a 4cm sized, markedly inflammatory, boggy mass on the occipital scalp. The second one showed several 2-3cm sized, erythematous, follicular pustules and plaques with partial hair loss on the frontal and parietal scalp. The diagnosis was established by histopathologic and mycologic studies that are KOH, fungus culture, slide culture and histopathologic exams of the lesional specimen. All the lesions of the patients were cleared with itraconazole for several weeks and short-term systemic steroid.