J
Jaime Fornaguera
Researcher at University of Costa Rica
Publications - 19
Citations - 1025
Jaime Fornaguera is an academic researcher from University of Costa Rica. The author has contributed to research in topics: Dopamine & Lesion. The author has an hindex of 12, co-authored 18 publications receiving 905 citations. Previous affiliations of Jaime Fornaguera include University of Düsseldorf.
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Differential effect of environment enrichment and social isolation on depressive-like behavior, spontaneous activity and serotonin and norepinephrine concentration in prefrontal cortex and ventral striatum
TL;DR: Specific variations in physical and social environment during early rearing lead to some behavioral and neurochemical alterations which might be relevant for understanding the role that neurodevelopmental and experiential factors could have in human depression.
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A detailed analysis of open-field habituation and behavioral and neurochemical antidepressant-like effects in postweaning enriched rats.
TL;DR: The current results suggest that differential rearing is not only a useful procedure to study behavioral plasticity or rigidity in response to early experience, but also to modeling some developmental protective or risk factors underlying depressive disorders.
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The effect of chronic fluoxetine on social isolation-induced changes on sucrose consumption, immobility behavior, and on serotonin and dopamine function in hippocampus and ventral striatum.
Juan C. Brenes,Jaime Fornaguera +1 more
TL;DR: It was found that fluoxetine restored isolation-increased sucrose consumption and immobility behavior, without affecting locomotor activity, which appeared slightly increased in isolated groups both treated and untreated.
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Effects of environmental enrichment and social isolation on sucrose consumption and preference: associations with depressive-like behavior and ventral striatum dopamine.
Juan C. Brenes,Jaime Fornaguera +1 more
TL;DR: The present data support previous findings regarding the effects of early life events upon reward-sensitivity and depressive-like behavior, and also provide further evidence about the relationship between these motivated behaviors and the likely role of ventral striatum dopamine in regulating them.
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Behavioural characterisation of chronic unpredictable stress based on ethologically relevant paradigms in rats
TL;DR: Analysis of observable and latent variables indicate that early-life stress impairs the arousal-inhibition system leading to augmented and persistent responses towards novel, rewarding, and mildly-threatening stimuli, accompanied by lower body-weight gain.