J
James C. Garbutt
Researcher at University of North Carolina at Chapel Hill
Publications - 91
Citations - 5847
James C. Garbutt is an academic researcher from University of North Carolina at Chapel Hill. The author has contributed to research in topics: Alcohol dependence & Thyrotropin-releasing hormone. The author has an hindex of 31, co-authored 91 publications receiving 5435 citations. Previous affiliations of James C. Garbutt include Dorothea Dix Hospital & Shiga University of Medical Science.
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Journal ArticleDOI
Pharmacotherapy for Adults With Alcohol Use Disorders in Outpatient Settings A Systematic Review and Meta-analysis
Daniel E Jonas,Halle R Amick,Cynthia Feltner,Georgiy Bobashev,Kathleen C. Thomas,Roberta Wines,Mimi M. Kim,Mimi M. Kim,Ellen Shanahan,C Elizabeth Gass,Cassandra J Rowe,James C. Garbutt +11 more
TL;DR: In this paper, the authors compared acamprosate to naltrexone and found no statistically significant difference between them for return to any drinking (RD, 0.14 to 0.03) or heavy drinking.
Journal ArticleDOI
Efficacy and Tolerability of Long-Acting Injectable Naltrexone for Alcohol Dependence: A Randomized Controlled Trial
James C. Garbutt,Henry R. Kranzler,Stephanie S. O'Malley,David R. Gastfriend,David R. Gastfriend,Helen M. Pettinati,Bernard L. Silverman,John W. Loewy,Elliot Ehrich +8 more
TL;DR: Data indicate that long-acting naltrexone can be of benefit in the treatment of alcohol dependence and resulted in reductions in heavy drinking among treatment-seeking alcohol-dependent patients during 6 months of therapy.
Pharmacotherapy for Adults With Alcohol-Use Disorders in Outpatient Settings
Daniel E Jonas,Halle R Amick,Cynthia Feltner,Georgiy Bobashev,Kathleen C. Thomas,Roberta Wines,Mimi M. Kim,Ellen Shanahan,C Elizabeth Gass,Cassandra J Rowe,James C. Garbutt +10 more
TL;DR: A systematic review and meta-analysis of the benefits and harms of medications for adults with alcohol use disorders found moderate evidence supports an association with improvement in some consumption outcomes for nalmefene and topiramate.
Journal ArticleDOI
Pharmacological treatment of alcohol dependence - A review of the evidence
TL;DR: Evaluating the efficacy of 5 categories of drugs used to treat alcohol dependence found some evidence that drinking frequency is reduced but minimal evidence to support improved continuous abstinence rates, and recent reports documenting that naltrexone and acamprosate are more effective than placebo justify clinical interest in use of these medications for alcohol-dependent patients.
Journal ArticleDOI
Behavioral counseling after screening for alcohol misuse in primary care: a systematic review and meta-analysis for the U.S. Preventive Services Task Force
Daniel E Jonas,James C. Garbutt,Halle R Amick,Janice M Brown,Kimberly A Brownley,Anthony J. Viera,Tania M Wilkins,Cody J Schwartz,Emily M Richmond,John Yeatts,Tammeka Swinson Evans,Sally D Wood,Russell Harris +12 more
TL;DR: Behavioral counseling interventions improve behavioral outcomes for adults with risky drinking and trials enrolling young adults or college students showed reduced consumption and fewer heavy drinking episodes.