J
James D. Folds
Researcher at University of North Carolina at Chapel Hill
Publications - 65
Citations - 2739
James D. Folds is an academic researcher from University of North Carolina at Chapel Hill. The author has contributed to research in topics: Immune system & Antigen. The author has an hindex of 26, co-authored 65 publications receiving 2678 citations. Previous affiliations of James D. Folds include Memorial Hospital of South Bend.
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Journal ArticleDOI
Progression to AIDS: the effects of stress, depressive symptoms, and social support.
Jane Leserman,Eric D. Jackson,John M. Petitto,Robert N. Golden,Susan G. Silva,Diana O. Perkins,Jianwen Cai,James D. Folds,Dwight L. Evans +8 more
TL;DR: Data are among the first to demonstrate that more stress and less social support may accelerate the course of HIV disease progression, and additional study will be necessary to elucidate the mechanisms that underlie these relationships.
Journal ArticleDOI
Impact of Stressful Life Events, Depression, Social Support, Coping, and Cortisol on Progression to AIDS
Jane Leserman,John M. Petitto,Robert N. Golden,Bradley N. Gaynes,Hongbin Gu,Diana O. Perkins,Susan G. Silva,James D. Folds,Dwight L. Evans +8 more
TL;DR: Faster progression to AIDS was associated with higher cumulative average stressful life events, coping by means of denial, and higher serum cortisol as well as with lower cumulative average satisfaction with social support and tobacco use, risky sexual behavior.
Journal ArticleDOI
Severe stress, depressive symptoms, and changes in lymphocyte subsets in human immunodeficiency virus-infected men. A 2-year follow-up study.
Jane Leserman,John M. Petitto,Diana O. Perkins,James D. Folds,Robert N. Golden,Dwight L. Evans +5 more
TL;DR: The findings are among the first prospective data showing that stress and depressive symptoms, especially when they occur jointly, are associated with decreased number of NK and CD8+ T lymphocytes in HIV-infected men.
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Severe life stress as a predictor of early disease progression in HIV infection
Dwight L. Evans,Jane Leserman,Diana O. Perkins,Robert S. Stern,Carol Murphy,Beiyao Zheng,David R. Gettes,Jeffrey A. Longmate,Susan G. Silva,Charles van der Horst,Colin D. Hall,James D. Folds,Robert N. Golden,John M. Petitto +13 more
TL;DR: Evidence is presented that severe life event stress is associated with an increased rate of early HIV disease progression, the first evidence from a prospective research study to do so.
Journal ArticleDOI
Circulating natural killer cell phenotypes in men and women with major depression. Relation to cytotoxic activity and severity of depression.
Dwight L. Evans,James D. Folds,John M. Petitto,Robert N. Golden,Cort A. Pedersen,Mark Corrigan,John H. Gilmore,Susan G. Silva,Dana Quade,Howard Ozer +9 more
TL;DR: In this paper, the effects of major depression on peripheral blood natural killer cell phenotypes and NCC activity were studied by comparing depressed and normal control subjects, and the findings suggest that alterations in the availability and the killing capacity of circulating Leu-11 natural killer cells appear to be responsible for depression-related reductions in NCC activation.