J
Jan Gummert
Researcher at Heart and Diabetes Center North Rhine-Westphalia
Publications - 358
Citations - 11610
Jan Gummert is an academic researcher from Heart and Diabetes Center North Rhine-Westphalia. The author has contributed to research in topics: Medicine & Internal medicine. The author has an hindex of 55, co-authored 290 publications receiving 10570 citations. Previous affiliations of Jan Gummert include Stanford University & Leipzig University.
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Journal ArticleDOI
Regular Physical Activity Improves Endothelial Function in Patients With Coronary Artery Disease by Increasing Phosphorylation of Endothelial Nitric Oxide Synthase
Rainer Hambrecht,Volker Adams,Sandra Erbs,Axel Linke,Nicolle Kränkel,Yanwen Shu,Yves Baither,Stephan Gielen,Holger Thiele,Jan Gummert,Friedrich-Wilhelm Mohr,Gerhard Schuler +11 more
TL;DR: Exercise training in stable CAD leads to an improved agonist-mediated endothelium-dependent vasodilatory capacity as well as a shear stress–induced/Akt-dependent phosphorylation of eNOS on Ser1177.
Journal ArticleDOI
Stroke after cardiac surgery: a risk factor analysis of 16,184 consecutive adult patients.
Jan Bucerius,Jan Gummert,Michael A. Borger,Thomas Walther,Nicolas Doll,Jörg F Onnasch,Sebastian Metz,Volkmar Falk,Friedrich W. Mohr +8 more
TL;DR: It is believed beating heart CABG is associated with a lower incidence of stroke and may therefore improve patient outcomes, and multivariable analysis revealed 10 variables that were independent predictors of stroke.
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Fibrosis in left atrial tissue of patients with atrial fibrillation with and without underlying mitral valve disease
Andreas Boldt,Ulrike Wetzel,J Lauschke,J Weigl,Jan Gummert,Gerhard Hindricks,H Kottkamp,Stefan Dhein +7 more
TL;DR: Enhanced concentrations of ECM proteins may have a role in structural remodelling and the pathogenesis of AF as a result of separation of the cells by fibrotic depositions.
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Computer-enhanced "robotic" cardiac surgery: experience in 148 patients
Friedrich W. Mohr,Volkmar Falk,Anno Diegeler,Thomas Walther,Jan Gummert,Jan Bucerius,Stefan Jacobs,Rüdiger Autschbach +7 more
TL;DR: Computer-enhanced endoscopic cardiac surgery can be performed safely in selected patients and internal thoracic artery takedown is now routinely performed with good results, according to a steep learning curve.
Journal ArticleDOI
Impact of Regular Physical Activity on the NAD(P)H Oxidase and Angiotensin Receptor System in Patients With Coronary Artery Disease
Volker Adams,Axel Linke,Nicolle Kränkel,Sandra Erbs,Stephan Gielen,Sven Möbius-Winkler,Jan Gummert,Friedrich W. Mohr,Gerhard Schuler,Rainer Hambrecht +9 more
TL;DR: ET reduces vascular expression of NAD(P)H oxidase and AT1-R, resulting in decreased local ROS generation and these molecular effects converge in a reduced Ang II–mediated vasoconstriction.