Jan Hasselström

TL;DR: Comparison of oral with intravenous excretion curves showed that a greater part of morphine and metabolites were excreted during the slowly declining phase after the oral dose than the intravenous dose, which is highly suggestive of enterohepatic cycling.

TL;DR: The acceptance of the 'Wise List' in terms of trust among physicians and among the public and increased adherence may be explained by clear criteria for drug recommendations, a comprehensive communication strategy, electronic access to recommendations, continuous medical education and involvement of professional networks and patients.

TL;DR: The prevalence and diagnostic pattern of pain at the primary care level during one year in a group practice serving the patients of a geographically defined area with approximately 14,000 inhabitants is estimated.

TL;DR: Clinically important findings were a high oral bioavailability and a long elimination half-life of morphine and the metabolism of morphine is impaired significantly in patients with severe cirrhosis.

TL;DR: There was no difference between PM and EM in the AUC of C6G and NCG, nor in the partial clearances by N-demethylation and glucuronidation, Norcodeine, norcodeine (NC), NC-glucuronide (NCG), morphine, and normorphine (NM) were investigated after a single oral dose of 50 mg codeine phosphate.