Jan Willem Berkelbach van der Sprenkel

TL;DR: Although case fatality after treatment has decreased over time, treatment of brain AVM remains associated with considerable risks and incomplete efficacy, and Randomized controlled trials comparing different treatment modalities appear justified.

TL;DR: It is demonstrated that poststroke loss and recovery of sensorimotor function is associated with acute deterioration and subsequent retrieval of interhemispheric functional connectivity within the sensorsimotor system, and the potential of rs-fMRI to assess spatiotemporal characteristics of functional brain reorganization that may underlie behavioral recovery after brain injury is underscored.

TL;DR: Once again, a randomized open-label, blinded-adjudication trial confirms that EC-IC bypass surgery offers no additional benefit to optimal medical therapy in patients with symptomatic carotid occlusive disease.

TL;DR: The degree of functional recovery after stroke is associated with the extent of preservation or restoration of ipsilesional corticospinal tracts in combination with reinstatement of interhemispheric neuronal signal synchronization and normalization of small-world cortical network organization.

TL;DR: There is no rationale for the routine use of neuronsavigation to improve the extent of tumor resection and prognosis in patients harboring a solitary enhancing intracerebral lesion when neuronavigation is not already deemed advantageous because of the size or location of the lesion.