J
Janet D. McConnell
Researcher at University College London
Publications - 4
Citations - 500
Janet D. McConnell is an academic researcher from University College London. The author has contributed to research in topics: Myosin & Tissue culture. The author has an hindex of 4, co-authored 4 publications receiving 497 citations. Previous affiliations of Janet D. McConnell include University of Melbourne.
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Comparison of vascular smooth muscle cells from adult human, monkey and rabbit in primary culture and in subculture.
TL;DR: A method is presented for growing large numbers of pure isolated smooth muscle cells from adult human, monkey, and rabbit blood vessels in primary culture to modify or “dedifferentiated” after about 9 days in culture to morphologically resemble fibroblasts.
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Comparison of the reaction of cultured smooth and cardiac muscle cells and fibroblasts to specific antibodies to myosin.
TL;DR: Immunofluorescent staining with anti-smooth or anti-striated muscle myosin is useful for distinguishing between isolated smooth muscle cells and fibroblasts in tissue culture.
Journal ArticleDOI
Tissue culture of mammalian enteric neurons.
Kristjan R. Jessen,Janet D. McConnell,Robert D. Purves,Geoffrey Burnstock,Julie H. Chamley-Campbell +4 more
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Membrane alteration of trypsin-treated smooth muscle cells and penetration by antibodies to myosin
TL;DR: It is concluded from these experiments that above a crucial trypsin concentration, the membrane becomes altered sufficiently to permit the penetration of antibodies into the cell interior.