J
Jason A. Poff
Researcher at National Institutes of Health
Publications - 2
Citations - 526
Jason A. Poff is an academic researcher from National Institutes of Health. The author has contributed to research in topics: Targeted drug delivery & Drug carrier. The author has an hindex of 2, co-authored 2 publications receiving 492 citations.
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Journal ArticleDOI
Pulsed-high intensity focused ultrasound and low temperature-sensitive liposomes for enhanced targeted drug delivery and antitumor effect.
Sergio Dromi,Victor Frenkel,Alfred Chun Shui Luk,Bryan Traughber,Mary Angstadt,Monica Bur,Jason A. Poff,Jianwu Xie,Steven K. Libutti,King C.P. Li,Bradford J. Wood +10 more
TL;DR: Combining low-temperature heat-sensitive liposomes with noninvasive and nondestructive pulsed-HIFU exposures enhanced the delivery of doxorubicin and, consequently, its antitumor effects.
Journal ArticleDOI
Pulsed High-Intensity Focused Ultrasound Enhances Apoptosis and Growth Inhibition of Squamous Cell Carcinoma Xenografts with Proteasome Inhibitor Bortezomib
Jason A. Poff,Clint T. Allen,Bryan Traughber,Aric Colunga,Jianwu Xie,Zhong Chen,Bradford J. Wood,Carter Van Waes,King C.P. Li,Victor Frenkel +9 more
TL;DR: Treatment of tumors with pulsed HIFU lowered the threshold level for efficacy of bortezomib, resulting in significant tumor cytotoxicity and growth inhibition at lower dose levels.