J
Jean Maritz
Researcher at National Health Laboratory Service
Publications - 25
Citations - 365
Jean Maritz is an academic researcher from National Health Laboratory Service. The author has contributed to research in topics: Medicine & Internal medicine. The author has an hindex of 9, co-authored 23 publications receiving 324 citations. Previous affiliations of Jean Maritz include Stellenbosch University & University of Cape Town.
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Journal ArticleDOI
HIV neuropathy in South Africans: Frequency, characteristics, and risk factors
Jean Maritz,Michael Benatar,Joel A. Dave,Taylor B. Harrison,Motasim Badri,Naomi S. Levitt,Jeannine M. Heckmann +6 more
TL;DR: The possibility that the incidence of DSP may be reduced with avoidance of stavudine‐containing regimens in older subjects, especially with a history of prior TB infection is raised.
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Establishing diagnostic cut-off criteria for the COBAS AmpliPrep/COBAS TaqMan HIV-1 Qualitative test through validation against the Amplicor DNA test v1.5 for infant diagnosis using dried blood spots.
TL;DR: The HIV-1 Qualitative test is a total nucleic acid real-time PCR assay utilising whole EDTA blood or dried blood spots and has a positive predictive value (PPV) of only 78.7% compared to the Amplicor assay, which is lower than the CAP/CTM's sensitivity and specificity.
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Recommendations for the management of indeterminate HIV PCR results within South Africa’s early infant diagnosis programme
Ahmad Haeri Mazanderani,Karl-Günter Technau,Nei-Yuan Hsiao,Jean Maritz,Sergio Carmona,Gayle G. Sherman +5 more
TL;DR: The extent of indeterminate HIV PCR results within South Africa’s early infant diagnosis programme is described and recommendations for the management of these cases are provided, both in terms of laboratory practice and the clinical care of the infants.
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Irreproducible positive results on the Cobas AmpliPrep/Cobas TaqMan HIV-1 Qual test are different qualitatively from confirmed positive results.
TL;DR: This retrospective, laboratory‐based study found that 193 of 211 patients with previous inconclusive results tested negative and only 18 tested positive using independently obtained follow‐up samples after a median of 28 days, suggesting the lower FI values in false‐positive compared to true‐positive results probably are indicative of a non‐specific signal.
Journal ArticleDOI
Rapid decline of HIV-1 DNA and RNA in infants starting very early antiretroviral therapy may pose a diagnostic challenge.
Kirsten A. Veldsman,Jean Maritz,Jean Maritz,Shahieda Isaacs,Mary Grace Katusiime,Anita Janse van Rensburg,Anita Janse van Rensburg,Barbara Laughton,Barbara Laughton,John W. Mellors,Mark F. Cotton,Mark F. Cotton,Gert U. van Zyl,Gert U. van Zyl +13 more
TL;DR: In infants initiated on ART within 8 days of life the combination of maternal ART, and early ART for prophylaxis and treatment contribute to rapid decline of HIV-1 infected cells to low or undetectable levels, which may complicate definitive diagnosis when confirmatory testing is delayed.