J
Jeong Chan Ra
Researcher at Seoul National University
Publications - 40
Citations - 1697
Jeong Chan Ra is an academic researcher from Seoul National University. The author has contributed to research in topics: Stem cell & Mesenchymal stem cell. The author has an hindex of 15, co-authored 40 publications receiving 1475 citations.
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Journal ArticleDOI
Safety of intravenous infusion of human adipose tissue-derived mesenchymal stem cells in animals and humans.
Jeong Chan Ra,Il Seob Shin,Sang Han Kim,Sung Keun Kang,Byeong Cheol Kang,Hang Young Lee,Youn Joung Kim,Jung Youn Jo,Eun Ji Yoon,Hyung Jun Choi,Euna Kwon +10 more
TL;DR: The systemic transplantation of hAdMSCs appears to be safe and does not induce tumor development, according to a human clinical trial and a tumorigenicity test in mice.
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Journey of mesenchymal stem cells for homing: strategies to enhance efficacy and safety of stem cell therapy.
TL;DR: This review of the state of current research on homing of MSCs suggests that favorable cellular conditions and the in vivo environment facilitate and are required for the migration of M SCs to the site of insult or injury in vivo.
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Enhanced proliferation and differentiation of Oct4- and Sox2-overexpressing human adipose tissue mesenchymal stem cells
Sei-Myoung Han,Sang-Hun Han,Ye-Rin Coh,Goo Jang,Jeong Chan Ra,Sung Keun Kang,Hee-Woo Lee,Hwa-Young Youn +7 more
TL;DR: The improvement in cell proliferation and differentiation using Oct4/Sox2 expression in ATMSCs may be a useful method for expanding the population and increasing the stemness of AT MSCs.
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Stem cell treatment for patients with autoimmune disease by systemic infusion of culture-expanded autologous adipose tissue derived mesenchymal stem cells.
Jeong Chan Ra,Sung Keun Kang,Il Seob Shin,Hyeong Geun Park,Sang Aun Joo,Jeong Geun Kim,Byeong Cheol Kang,Yong Soon Lee,Ken Nakama,Min Piao,Bertram Sohl,Andras Kurtz +11 more
TL;DR: The data provide convincing evidence for safety and therapeutic properties of systemically administered AdMSC in human patients with no other treatment options, and the authors believe that ex-vivo-expanded autologous AdMSCs provide a promising alternative for treating autoimmune diseases.
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Reversal of serologic, immunologic, and histologic dysfunction in mice with systemic lupus erythematosus by long-term serial adipose tissue-derived mesenchymal stem cell transplantation.
Eun Wha Choi,Il Seob Shin,So Young Park,Ji Hyun Park,Jong Sung Kim,Eun Ji Yoon,Sung Keun Kang,Jeong Chan Ra,Sung Hwa Hong +8 more
TL;DR: Serial human AD-MSC transplantation had beneficial effects in the treatment of SLE, without adverse effects, and before disease onset was preferable for amelioration of Sle and restoration of immune homeostasis.