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Ji Zhang

Researcher at Peking University

Publications -  32
Citations -  1271

Ji Zhang is an academic researcher from Peking University. The author has contributed to research in topics: Cancer & Medicine. The author has an hindex of 10, co-authored 29 publications receiving 1030 citations. Previous affiliations of Ji Zhang include Dalian Medical University & University of California, San Francisco.

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Gene expression patterns of human colon tops and basal crypts and BMP antagonists as intestinal stem cell niche factors.

TL;DR: This study suggests that BMP antagonists are candidate signaling components that make up the intestinal epithelial stem cell niche, and applies gene expression analysis of normal human colon tops and basal crypts to provide a comprehensive picture of human colonic epithelial cell differentiation.
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Array-based comparative genomic hybridization reveals recurrent chromosomal aberrations and Jab1 as a potential target for 8q gain in hepatocellular carcinoma.

TL;DR: This study shows that array-based CGH provides high resolution mapping of chromosomal aberrations in HCC, and demonstrates the feasibility of correlating array CGH data with gene expression data to identify novel oncogenes and tumor suppressor genes.
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Reduced expression of EphB2 that parallels invasion and metastasis in colorectal tumours

TL;DR: A progressive loss of EphB2 expression in each critical step of colon carcinogenesis, including the onset of invasion, dedifferentiation and metastasis is demonstrated which is paralleled by adverse patient outcome.
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Hedgehog signaling in human hepatocellular carcinoma.

TL;DR: Evidence that hedgehog signaling may be activated in some HCC tumors is provided for the first time and the results indicate that the hedgehog pathway may be a new candidate for therapeutic targeting in HCC.
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The 8th edition of the American Joint Committee on Cancer tumor-node-metastasis staging system for gastric cancer is superior to the 7th edition: results from a Chinese mono-institutional study of 1663 patients.

TL;DR: The 8th edition of the tumor-node-metastasis (TNM) system is superior to the 7th edition system in terms of homogeneity, discriminatory ability, and monotonicity of gradients for Chinese patients with gastric cancer.