J
Jin Yao
Researcher at Nanjing Medical University
Publications - 63
Citations - 5766
Jin Yao is an academic researcher from Nanjing Medical University. The author has contributed to research in topics: Medicine & Retinal pigment epithelium. The author has an hindex of 25, co-authored 51 publications receiving 2464 citations.
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Journal ArticleDOI
Repertoires of Autophagy in the Pathogenesis of Ocular Diseases
TL;DR: In this manuscript, the relevant progress about the role of autophagy in the pathogenesis of ocular diseases is reviewed and pharmacological manipulation of Autophagy may provide an alternative therapeutic target for some Ocular diseases.
Journal ArticleDOI
lncRNA-MIAT Regulates Microvascular Dysfunction by Functioning as a Competing Endogenous RNA
Biao Yan,Jin Yao,Jing-Yu Liu,Xiu-Miao Li,Xiao-Qun Wang,Yu-Jie Li,Zhi-Fu Tao,Yu-Chen Song,Qi Chen,Qin Jiang +9 more
TL;DR: This study highlights the involvement of lNCRNA-MIAT in pathological angiogenesis and facilitates the development of lncRNA-directed diagnostics and therapeutics against neovascular diseases.
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Pathogenic role of lncRNA-MALAT1 in endothelial cell dysfunction in diabetes mellitus
TL;DR: It is shown that MALAT1 expression is significantly upregulated in the retinas of STZ-induced diabetic rats and db/db mice, which represents a critical pathogenic mechanism for diabetes-induced microvascular dysfunction.
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Salvianolic acid A protects RPE cells against oxidative stress through activation of Nrf2/HO-1 signaling
TL;DR: Observations suggest that Sal A activates the Nrf2/HO-1 axis in RPE cells and protects against oxidative stress via activation of Akt/mTORC1 signaling.
Journal ArticleDOI
Silencing Of Circular RNA-ZNF609 Ameliorates Vascular Endothelial Dysfunction.
Chang Liu,Chang Liu,Mu-Di Yao,Chao-Peng Li,Kun Shan,Hong Yang,Jia-Jian Wang,Ban Liu,Xiu-Miao Li,Jin Yao,Qin Jiang,Biao Yan +11 more
TL;DR: It is revealed that cZNF609 was significantly up-regulated upon high glucose and hypoxia stress in vivo and in vitro, and intervention of cZ NF609 expression is promising therapy for vascular dysfunction.