J
Jinghui Sun
Researcher at Beihua University
Publications - 52
Citations - 613
Jinghui Sun is an academic researcher from Beihua University. The author has contributed to research in topics: Schisandra & Schisandra chinensis. The author has an hindex of 10, co-authored 50 publications receiving 311 citations.
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Journal ArticleDOI
Protective effect of acidic polysaccharide from Schisandra chinensis on acute ethanol-induced liver injury through reducing CYP2E1-dependent oxidative stress
Rongshuang Yuan,Xue Tao,Shuang Liang,Yan Pan,Li He,Jinghui Sun,Ju Wenbo,Xiangyan Li,Jianguang Chen,Chunmei Wang +9 more
TL;DR: Schisandra chinensis acidic polysaccharide has a protective effect on ethanol-induced liver injury in mice and cells, and the mechanism underlying may be via inhibiting the expression of CYP2E1 protein and then alleviating oxidative stress injury induced by ethanol.
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Anti-fatigue effect of anwulignan via the NRF2 and PGC-1α signaling pathway in mice.
Xinyun Zhang,Shu Jing,Huijiao Lin,Wei Sun,Weihai Jiang,Chunyan Yu,Jinghui Sun,Chunmei Wang,Jianguang Chen,He Li +9 more
TL;DR: Anwulignan can increase exercise tolerance and relieve fatigue in an excessive fatigue mouse model and the underlying mechanism may be through its regulatory effect on the NRF2 and PGC-1α signaling pathway.
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Schisandra polysaccharide inhibits hepatic lipid accumulation by downregulating expression of SREBPs in NAFLD mice
TL;DR: The hepatoprotective effects of Schisandra polysaccharide in a mouse model of non-alcoholic fatty liver disease (NAFLD) are demonstrated; the effects may be mediated via downregulation of LXRα/SREBP-1c/FAS/ACC and SRE BP-2/HMGCR signaling pathways in the liver.
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Metabolomics study of the therapeutic mechanism of Schisandra Chinensis lignans in diet-induced hyperlipidemia mice
TL;DR: Anti-hyperlipidemia effect of SCL was confirmed by both serum biochemistry and metabolomics analysis and the mechanism may be related to the down-regulation of LXRα/SREBP-1c/FAS/ACC and SREBP2/HMGCR signaling pathways.
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Sedative and hypnotic effects of Schisandrin B through increasing GABA/Glu ratio and upregulating the expression of GABAA in mice and rats.
Ning Li,Jiale Liu,Mengyang Wang,Zepeng Yu,Kuo Zhu,Jiaqi Gao,Chunmei Wang,Jinghui Sun,Jianguang Chen,He Li +9 more
TL;DR: SchB is the active component in Schisandra chinensis Baill responsible for the sedative and hypnotic function through up-regulating the expression of GABAA receptors and modulating the content of GABA and Glu in the peripheral blood and brain tissues.