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Joana F. Guerreiro

Researcher at Instituto Superior Técnico

Publications -  29
Citations -  899

Joana F. Guerreiro is an academic researcher from Instituto Superior Técnico. The author has contributed to research in topics: Yeast & Zygosaccharomyces bailii. The author has an hindex of 11, co-authored 22 publications receiving 723 citations. Previous affiliations of Joana F. Guerreiro include German Cancer Research Center & Technical University of Lisbon.

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The YEASTRACT database: an upgraded information system for the analysis of gene and genomic transcription regulation in Saccharomyces cerevisiae

TL;DR: The YEASTRACT information system was revisited and new information was added on the experimental conditions in which those associations take place and on whether the TF is acting on its target genes as activator or repressor, allowing the selection of specific environmental conditions, experimental evidence or positive/negative regulatory effect.
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Genome-wide identification of Saccharomyces cerevisiae genes required for tolerance to acetic acid

TL;DR: The increase of potassium concentration in the growth medium was found to improve the expression of maximal tolerance to acetic acid, consistent with the idea that the adequate manipulation of nutrient concentration of industrial growth medium can be an interesting strategy to surpass the deleterious effects of this weak acid in yeast cells.
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Adaptive Response and Tolerance to Acetic Acid in Saccharomyces cerevisiae and Zygosaccharomyces bailii: A Physiological Genomics Perspective.

TL;DR: This review paper emphasizes genome-wide strategies that are providing global insights into the molecular targets, signaling pathways and mechanisms behind S. cerevisiae and Z. bailii tolerance to acetic acid, and extends this information to other weak acids whenever relevant.
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The genome sequence of the highly acetic acid-tolerant zygosaccharomyces bailii-derived interspecies hybrid strain ISA1307, isolated from a sparkling wine plant

TL;DR: The analysis of the genome sequence indicates that strain ISA1307 is an interspecies hybrid between Z. bailii and a closely related species, paving the way to a better understanding of the genetic mechanisms underlying the generation and selection of more robust hybrid yeast strains in the stressful environment of wine fermentations.
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Sphingolipid biosynthesis upregulation by TOR complex 2–Ypk1 signaling during yeast adaptive response to acetic acid stress

TL;DR: It is demonstrated that appropriate modulation of the TORC2-Ypk1-sphingolipid axis in industrial yeast strains may have utility in improving fermentations of acetic acid-containing feedstocks and promoting sphingolIPid synthesis by adding exogenous long-chain base precursor phytosphingosine to the growth medium enhanced acetic Acid tolerance.