https://www.ackdjournal.org/article/S1548-5595(06)00163-7/pdf

The Prevalence of Symptoms in End-Stage Renal Disease: A Systematic Review

T1 mapping allows direct in-vivo quantitation of microscopic changes in the myocardium, providing new diagnostic insights into cardiac disease. Existing methods require long breath holds that are demanding for many cardiac patients. In this work we propose and validate a novel, clinically applicable, pulse sequence for myocardial T1-mapping that is compatible with typical limits for end-expiration breath-holding in patients. The Shortened MOdified Look-Locker Inversion recovery (ShMOLLI) method uses sequential inversion recovery measurements within a single short breath-hold. Full recovery of the longitudinal magnetisation between sequential inversion pulses is not achieved, but conditional interpretation of samples for reconstruction of T1-maps is used to yield accurate measurements, and this algorithm is implemented directly on the scanner. We performed computer simulations for 100 ms<T1 < 2.7 s and heart rates 40-100 bpm followed by phantom validation at 1.5T and 3T. In-vivo myocardial T1-mapping using this method and the previous gold-standard (MOLLI) was performed in 10 healthy volunteers at 1.5T and 3T, 4 volunteers with contrast injection at 1.5T, and 4 patients with recent myocardial infarction (MI) at 3T. We found good agreement between the average ShMOLLI and MOLLI estimates for T1 < 1200 ms. In contrast to the original method, ShMOLLI showed no dependence on heart rates for long T1 values, with estimates characterized by a constant 4% underestimation for T1 = 800-2700 ms. In-vivo, ShMOLLI measurements required 9.0 ± 1.1 s (MOLLI = 17.6 ± 2.9 s). Average healthy myocardial T1 s by ShMOLLI at 1.5T were 966 ± 48 ms (mean ± SD) and 1166 ± 60 ms at 3T. In MI patients, the T1 in unaffected myocardium (1216 ± 42 ms) was similar to controls at 3T. Ischemically injured myocardium showed increased T1 = 1432 ± 33 ms (p < 0.001). The difference between MI and remote myocardium was estimated 15% larger by ShMOLLI than MOLLI (p < 0.04) which suffers from heart rate dependencies for long T1. The in-vivo variability within ShMOLLI T1-maps was only 14% (1.5T) or 18% (3T) higher than the MOLLI maps, but the MOLLI acquisitions were twice longer than ShMOLLI acquisitions. ShMOLLI is an efficient method that generates immediate, high-resolution myocardial T1-maps in a short breath-hold with high precision. This technique provides a valuable clinically applicable tool for myocardial tissue characterisation.

/pdf/shortened-modified-look-locker-inversion-recovery-shmolli-38kstdiqr8.pdf

Shortened Modified Look-Locker Inversion recovery (ShMOLLI) for clinical myocardial T1-mapping at 1.5 and 3 T within a 9 heartbeat breathhold

Over the past three decades, cognitive-behavioral therapy (CBT) has become a first-line psychosocial treatment for individuals with chronic pain. Evidence for efficacy in improving pain and pain-related problems across a wide spectrum of chronic pain syndromes has come from multiple randomized controlled trials. CBT has been tailored to, and found beneficial for, special populations with chronic pain, including children and older adults. Innovations in CBT delivery formats (e.g., Web-based, telephone-delivered) and treatments based on CBT principles that are delivered by health professionals other than psychologists show promise for chronic pain problems. This article reviews (a) the evidence base for CBT as applied to chronic pain, (b) recent innovations in target populations and delivery methods that expand the application of CBT to underserved populations, (c) current limitations and knowledge gaps, and (d) promising directions for improving CBT efficacy and access for people living with chronic pain.

/pdf/cognitive-behavioral-therapy-for-individuals-with-chronic-1ja4okwa15.pdf

Cognitive-behavioral therapy for individuals with chronic pain: efficacy, innovations, and directions for research.

Anxiety and Depression in COPD: Current Understanding, Unanswered Questions, and Research Needs

This systematic evidence review supports the American College of Physicians guideline on palliative care at the end of life. Strong to moderate evidence supports use of various treatments for cance...

Evidence for Improving Palliative Care at the End of Life: A Systematic Review

https://www.jpsmjournal.com/article/S0885-3924(05)00561-0/pdf

A comparison of symptom prevalence in far advanced cancer, AIDS, heart disease, chronic obstructive pulmonary disease and renal disease

Over recent years attention has been paid to the need to broaden the concept of palliative care and to include the grief reactions of patients’ family members as a focus of multiprofessional teams. In hospitals, grief affects not just the patient who receives the news of a reserved prognosis, but also the patient’s family and the technical teams who come into contact with the patient. Due to its potential to become complicated and cause physical, psychological and community problems, grief has already been identified as a public health problem, capable of silently placing a burden on care networks. This article aims to locate the problem of grief in hospital palliative care and oncology teams and give an overview of a group assistance program for grieving family members which has contributed to an improvement in the quality of communication and the dissemination of information in a teaching hospital in São Paulo.

Grief on the Agenda of Multiprofessional Oncology and Palliative Care Teams: a Family Assistance Program at the Federal University of São Paulo

Over recent years attention has been paid to the need to broaden the concept of palliative care and to include the grief reactions of patients’ family members as a focus of multiprofessional teams. In hospitals, grief affects not just the patient who receives the news of a reserved prognosis, but also the patient’s family and the technical teams who come into contact with the patient. Due to its potential to become complicated and cause physical, psychological and community problems, grief has already been identified as a public health problem, capable of silently placing a burden on care networks. This article aims to locate the problem of grief in hospital palliative care and oncology teams and give an overview of a group assistance program for grieving family members which has contributed to an improvement in the quality of communication and the dissemination of information in a teaching hospital in Sao Paulo.

/pdf/o-luto-na-agenda-das-equipes-multiprofissionais-de-oncologia-3vr9uhjfev.pdf

O luto na agenda das equipes multiprofissionais de oncologia e cuidados paliativos: apresentação de um Programa de Assistência a Familiares na Universidade Federal de São Paulo

João Paulo Consentino Solano

Papers

A comparison of symptom prevalence in far advanced cancer, AIDS, heart disease, chronic obstructive pulmonary disease and renal disease

Grief on the Agenda of Multiprofessional Oncology and Palliative Care Teams: a Family Assistance Program at the Federal University of São Paulo

O luto na agenda das equipes multiprofissionais de oncologia e cuidados paliativos: apresentação de um Programa de Assistência a Familiares na Universidade Federal de São Paulo