Jody Schock

TL;DR: In patients with treatment-induced suppression of blood viral load the likelihood of having detectable HIV in semen is very low (< 4%), and seminal shedding of cell-free and cell-associated HIV is significantly lower than in an untreated population of HIV-infected asymptomatic men.

TL;DR: The results indicate that alteredcoreceptor usage is rare in subtype C HIV-1 isolates in sub-Saharan Africa and that sequence variability is not a feature of the V3 region of env in the absence of altered coreceptor usage.

TL;DR: It is demonstrated that viral loads in nonblood fluids were generally lower than in blood, and NASBA worked fairly well to quantitate HIV-1 RNA from all fluids without apparent inhibition.

TL;DR: High levels of human immunodeficiency virus type 1 (HIV-1) replication, as reflected in HIV-1 RNA concentrations in blood and semen, probably contribute to both rapid disease progression and enhanced sexual transmission in sub-Saharan Africa.

TL;DR: Comparison of whole blood dried on filter paper to the standard assay with frozen cell-free plasma for use in the quantitation of the human immunodeficiency virus RNA load in blood gave results comparable to those of thestandard assay in terms of sensitivity and reproducibility.