J
John L. Plummer
Researcher at Flinders Medical Centre
Publications - 136
Citations - 5144
John L. Plummer is an academic researcher from Flinders Medical Centre. The author has contributed to research in topics: Patient-controlled analgesia & Palliative care. The author has an hindex of 40, co-authored 136 publications receiving 4926 citations. Previous affiliations of John L. Plummer include Duke University & Flinders University.
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Journal ArticleDOI
Fentanyl blood concentration-analgesic response relationship in the treatment of postoperative pain.
Geoffrey K. Gourlay,Stefan R. Kowalski,John L. Plummer,Michael J. Cousins,Peter J. Armstrong +4 more
TL;DR: The large fluctuations in the hourly fentanyl dose rate do not accurately reflect the relatively constant blood concentration-analgesic effect relationship, and care is necessary in the use of mean hourly fentanyl doses derived from PCA infusions as indexes of pharmacodynamic effects, especially pain relief.
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Preference for place of care and place of death in palliative care: are these different questions?:
Meera Agar,David C. Currow,Tania Maree Shelby-James,John L. Plummer,Christine Sanderson,Amy P. Abernethy +5 more
TL;DR: This study suggests that there are two conversations: preference for current place of care and preference for care at the time of death, and further research is needed to delineate these.
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Prescribing in Palliative Care as Death Approaches
TL;DR: To determine how prescribing for comorbid illnesses and symptom control changes during the palliative phase of a terminal illness is determined, a large number of patients with a history of cancer are referred for treatment.
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Randomized, Double-Blind, Placebo-Controlled Study to Assess the Efficacy and Toxicity of Subcutaneous Ketamine in the Management of Cancer Pain
Janet Hardy,Stephen Quinn,Belinda Fazekas,John L. Plummer,Simon Eckermann,Meera Agar,Odette Spruyt,Debra Rowett,David C. Currow +8 more
TL;DR: Ketamine does not have net clinical benefit when used as an adjunct to opioids and standard coanalgesics in cancer pain and is considered of net benefit if it provided clinically relevant improvement in pain with limited breakthrough analgesia and acceptable toxicity.
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Pharmacokinetics of fentanyl in lumbar and cervical CSF following lumbar epidural and intravenous administration.
Geoffrey K. Gourlay,Terence M. Murphy,John L. Plummer,Stefan R. Kowalski,David A. Cherry,M. J. Cousins +5 more
TL;DR: Fentanyl is rapidly absorbed across the dura mater following epidural administration providing significant lumbar CSF concentrations, and the role of cervical fentanyl concentrations to any pharmacological effects remains unresolved.