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John R. Stratton

Researcher at University of Washington

Publications -  98
Citations -  6315

John R. Stratton is an academic researcher from University of Washington. The author has contributed to research in topics: Heart rate & Myocardial infarction. The author has an hindex of 43, co-authored 98 publications receiving 6141 citations. Previous affiliations of John R. Stratton include John Radcliffe Hospital & Harborview Medical Center.

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Cardiovascular responses to exercise. Effects of aging and exercise training in healthy men.

TL;DR: There is an age-associated decline in heart rate, ejection fraction, and cardiac output responses to supine exercise in healthy men and both the young and old increased peak exercise cardiac output by use of the Frank-Starling mechanism (ie, cardiac dilatation) as well as an increase in ejectedion fraction.
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Physical training improves skeletal muscle metabolism in patients with chronic heart failure

TL;DR: The reduction in phosphocreatine depletion and in the increase in ADP during exercise, and the enhanced rate of phosphocreatingine resynthesis in recovery indicate that a substantial correction of the impaired oxidative capacity of skeletal muscle in chronic heart failure can be achieved by exercise training.
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Mechanisms of thrombocytopenia in chronic autoimmune thrombocytopenic purpura. Evidence of both impaired platelet production and increased platelet clearance.

TL;DR: Both depressed platelet production and increased platelet clearance by the liver and spleen contribute to the thrombocytopenia of AITP.
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Detection of left ventricular thrombus by two-dimensional echocardiography: sensitivity, specificity, and causes of uncertainty.

TL;DR: Patients with proved thrombus had a higher prevalence of electrocardiographic transmural anterior infarction, left ventricular aneurysm, and clinical systemic emboli and these clinical features help to identify a subset of patients most likely to haveleft ventricular thrombi who may benefit from echocardiography.
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Effect of endurance exercise training on heart rate variability at rest in healthy young and older men

TL;DR: Exercise training increases parasympathetic tone at rest in both the healthy older and young men, which may contribute to the reduction in mortality associated with regular exercise.