J
Jonathan A. Borden
Researcher at Tufts Medical Center
Publications - 10
Citations - 3237
Jonathan A. Borden is an academic researcher from Tufts Medical Center. The author has contributed to research in topics: Interphase & Karyotype. The author has an hindex of 9, co-authored 10 publications receiving 3112 citations. Previous affiliations of Jonathan A. Borden include Yale University.
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Delineation of individual human chromosomes in metaphase and interphase cells by in situ suppression hybridization using recombinant DNA libraries
TL;DR: A method of in situ hybridization for visualizing individual human chromosomes from pter to qter, both in metaphase spreads and interphase nuclei, is reported and should be useful for both karyotypic studies and for the analysis of chromosome topography in interphase cells.
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A proposed classification for spinal and cranial dural arteriovenous fistulous malformations and implications for treatment
TL;DR: A classification is proposed that unifies and organizes spinal and cranial dural arteriovenous fistulous malformations (AVFMs) into three types based upon their anatomical similarities.
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Detection of chromosome aberrations in metaphase and interphase tumor cells by in situ hybridization using chromosome-specific library probes
TL;DR: Analysis of chromosome aberrations in two glioma cell lines using biotinylated DNA library probes indicates the power of these methods for pinpointing chromosome segments that are altered in specific types of tumors.
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Reproducible compartmentalization of individual chromosome domains in human CNS cells revealed by in situ hybridization and three-dimensional reconstruction.
TL;DR: It is suggested that centromeric and other highly repeated non-transcribed sequence domains may act as general organizing centers for cell type specific interphase patterns that are conserved in mammalian evolution.
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Movement of the X chromosome in epilepsy
TL;DR: Optical sectioning provided a rapid method for three-dimensional resolution of in situ hybridization signals in interphase cells, and solid models were reconstructed from digitized images for detailed rotational studies.