J
Jordi Ortuño
Researcher at Autonomous University of Barcelona
Publications - 37
Citations - 2681
Jordi Ortuño is an academic researcher from Autonomous University of Barcelona. The author has contributed to research in topics: MDMA & Bioequivalence. The author has an hindex of 26, co-authored 36 publications receiving 2560 citations.
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Journal ArticleDOI
Non‐linear pharmacokinetics of MDMA (‘ecstasy’) in humans
R. de la Torre,Magí Farré,Jordi Ortuño,Marta Mas,Rudolf Brenneisen,Pere N. Roset,Jordi Segura,Jordi Camí +7 more
TL;DR: The lack of linearity of MDMA pharmacokinetics (in a window of doses compatible with its recreational use) is a more general phenomenon as it concerns the whole population independent of their CYP2D6 genotype.
Journal Article
Cardiovascular and Neuroendocrine Effects and Pharmacokinetics of 3,4-Methylenedioxymethamphetamine in Humans
TL;DR: The cardiovascular and neuroendocrine effects and pharmacokinetics of 3,4-methylenedioxymethamphetamine (MDMA, "ecstasy") were assessed in a double-blind, randomized, crossover, and controlled clinical trial.
Journal ArticleDOI
Hydroxytyrosol Disposition in Humans
Elisabet Miró-Casas,María Isabel Covas,Magí Farré,Montserrat Fitó,Jordi Ortuño,Tanja Weinbrenner,Pere N. Roset,Rafael de la Torre +7 more
TL;DR: From the results, approximately 98% of hydroxytyrosol appears to be present in plasma and urine in conjugated forms, mainly glucuronoconjugates, suggesting extensive first-pass intestinal/hepatic metabolism of the ingested hydroxyTYrosol.
Journal ArticleDOI
3,4-Methylenedioxymethamphetamine (Ecstasy) and Alcohol Interactions in Humans: Psychomotor Performance, Subjective Effects, and Pharmacokinetics
Cándido Hernández-López,Magí Farré,Pere N. Roset,E. Menoyo,Nieves Pizarro,Jordi Ortuño,Marta Torrens,Jordi Camí,Rafael de la Torre +8 more
TL;DR: MDMA reversed the subjective sedation induced by alcohol but did not reduce drunkenness feelings, and the MDMA-alcohol combination induced longer lasting euphoria and well being than MDMA or alcohol alone.
Journal ArticleDOI
Pharmacology of MDMA in Humans
R. de la Torre,Magí Farré,Pere N. Roset,C. Hernández López,Marta Mas,Jordi Ortuño,E. Menoyo,Neus Pizarro,Jordi Segura,Jordi Camí +9 more
TL;DR: Drug concentrations increased, and a parallel increase in physiologic and hormonal measures was observed, and MDMA induced a slight dose‐dependent impairment on psychomotor performance.