J
Joris R. Delanghe
Researcher at Ghent University
Publications - 576
Citations - 17081
Joris R. Delanghe is an academic researcher from Ghent University. The author has contributed to research in topics: Haptoglobin & Population. The author has an hindex of 62, co-authored 537 publications receiving 15263 citations. Previous affiliations of Joris R. Delanghe include Ghent University Hospital & Research Foundation - Flanders.
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Journal ArticleDOI
Biological and clinical significance of haptoglobin polymorphism in humans.
TL;DR: The strong genetic pressure favoring the 2-2 phenotype suggests an important role of haptoglobin in human pathology and is explained by a phenotype-dependent modulation of oxidative stress and prostaglandin synthesis.
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Lowered ω3 polyunsaturated fatty acids in serum phospholipids and cholesteryl esters of depressed patients
Michael Maes,Armand Christophe,Joris R. Delanghe,Carlo Altamura,Hugo Neels,Herbert Y. Meltzer +5 more
TL;DR: There is an abnormal metabolism of omega3 PUFAs in depression and the FA alterations in depression are related to the inflammatory response in that illness; and the disorders may persist despite successful antidepressant treatment.
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Biological and clinical aspects of the vitamin D binding protein (Gc-globulin) and its polymorphism
TL;DR: DBP is a highly polymorphic serum protein with three common alleles (Gc1F, Gc1S and Gc2) and more than 120 rare variants that are a useful tool for anthropological studies to discriminate and to reveal ancestral links between populations.
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Haptoglobin polymorphism, iron metabolism and mortality in HIV infection.
Joris R. Delanghe,Michel Langlois,Johan R. Boelaert,J Van Acker,F. Van Wanzeele,G van der Groen,Robert Hemmer,Chris Verhofstede,M. De Buyzere,Dirk De Bacquer,Vic Arendt,Jean Plum +11 more
TL;DR: To determine changes in chemokine and receptor expression in HIV infection, a large number of patients with or without HIV received chemotherapy for at least two weeks before and after treatment with antiretroviral drugs.
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Cloning of 16S rRNA genes amplified from normal and disturbed vaginal microflora suggests a strong association between Atopobium vaginae , Gardnerella vaginalis and bacterial vaginosis
Rita Verhelst,Hans Verstraelen,Geert Claeys,Gerda Verschraegen,Joris R. Delanghe,Leen Van Simaey,Catharine De Ganck,Marleen Temmerman,Mario Vaneechoutte +8 more
TL;DR: Results obtained by combining culture and PCR-based methods to characterize the normal and disturbed vaginal microflora indicate that much is to be learned about the composition of the vaginalmicroflora and its relation to the etiology of BV.