José Cruzado

TL;DR: Subjects in the FIT group were more likely to participate in screening than were those in the colonoscopy group, and more adenomas were identified in thecolorectal cancer group.

TL;DR: LSPs, but not proximal serrated polyps, are associated with the presence of synchronous advanced neoplasia, and further studies are needed to determine the risk of proximal hyperplastic polyps.

TL;DR: Women were more likely to participate in a FIT-based strategy, especially those aged 50–59 years, and the likelihood of detection of any neoplasm was higher in the colonoscopy arm for all the population groups studied, especially in women aged 50-59 years.

TL;DR: Whereas the NORCCAP criteria achieved the highest sensitivity for APN detection, the UK recommendations benefited from the lowest number of individuals needed to refer for colonoscopy.

TL;DR: To improve the performance of FIT in CRC screening programs, FIT cut-offs could be individualized by age and gender.