Jose Maria Casellas

TL;DR: ESBL-producing gram-negative bacilli were found to truly be multiresistant pathogens and were resistant to all -lactam antibiotics, most aminoglycosides, trimethoprimsulfamethoxazole, and sometimes the fluoroquinolones.

TL;DR: It is clinically important to detect ESBL production by klebsiellae or E. coli even when cephalosporin MICs are in the susceptible range (≤ 8 μg/ml) and to report ESBL-producing organisms as resistant to aztreonam and all cep Halosporins (with the exception of cephamycins).

TL;DR: Multivariate analysis including other predictors of mortality showed that use of a carbapenem during the 5-day period after onset of bacteremia due to an ESBL-producing organism was independently associated with lower mortality.

TL;DR: A distinctive form of K. pneumoniae infection, often causing liver abscess, was identified, almost exclusively in Taiwan.

TL;DR: A prospective study of Klebsiella pneumoniae bacteremia revealed a close relationship between ESBL production and ciprofloxacin resistance, which is particularly worrisome because the first reported instance of plasmid-mediated ciprafloxACin resistance has been in an isolate of K. pneumoniae also possessing an ESBL.