J
Joseph F. Hoffman
Researcher at Yale University
Publications - 86
Citations - 4826
Joseph F. Hoffman is an academic researcher from Yale University. The author has contributed to research in topics: Na+/K+-ATPase & Ouabain. The author has an hindex of 31, co-authored 86 publications receiving 4721 citations.
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Studies on the mechanism by which cyanine dyes measure membrane potential in red blood cells and phosphatidylcholine vesicles.
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Rapid photolytic release of adenosine 5'-triphosphate from a protected analogue: utilization by the Na:K pump of human red blood cell ghosts.
TL;DR: The caged ATP can be used as a stable source of ATP unmetabolizable by intracellular ATPases until the ATP is released following photolytic irradiation.
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Characterization of a new photoaffinity derivative of ouabain: labeling of the large polypeptide and of a proteolipid component of the Na, K-ATPase.
TL;DR: The results of the characterization of NAB-ouabain show that it has the required specificity, covalency, and efficiency of labeling for application in structural studies of Na,K-ATPase subunit interactions.
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Ionic and Osmotic Equilibria of Human Red Blood Cells Treated with Nystatin
TL;DR: By modifying the Jacobs-stewart equations with the osmotic coefficients of Hb and of salts, a nonideal thermodynamic model has been devised which predicts equilibrium Donnan ratios and red cell volume from the composition of the extracellular solution and from certain parameters of the cells.