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Medium chain fatty acid metabolism and energy expenditure: Obesity treatment implications

Synthetic low and high fat diets for the study of atherosclerosis in the mouse.

Lipid Biosynthesis in the Chick. A Consideration of Site of Synthesis, Influence of Diet and Possible Regulatory Mechanisms

The usefulness of dietary medium-chain triglycerides in body weight control: fact or fancy?

Publisher Summary This chapter discusses the interactions of environment and genetics in the development of obesity. There are major additions to the neuroanatomic basis for control of insulin secretion in response to nutrient intake. It is recognized that brain peptides act as both stimulators and inhibitors of feeding. The response of the autonomic nervous system to food intake and deprivation and the role this plays in the regulation of obesity is reviewed. The adrenalectomy is known to attenuate the development of all types of experimental obesity. The regulation of body fat stores and the development of obesity are viewed as problems of disturbed nutrient ingestion, disturbed energy expenditure, and disturbed internal balancing of these two processes. The models of experimental obesity provide insight into the control systems regulating body nutrient stores in humans. In this homeostatic or feed-back approach to analysis of the nutrient control system, the afferent feedback signals, the central controller, and the efferent control elements regulating the controlled system of nutrient intake, storage, and oxidation are examined.

Experimental obesity: a homeostatic failure due to defective nutrient stimulation of the sympathetic nervous system.

Influence of dietary lipid on lipogenesis and on the activity of malic enzyme and citrate cleavage enzyme in liver of the growing chick.

Significance of insulin in the metabolic adaptation of rats to meal ingestion.

Metabolic consequences of dietary medium-chain triglycerides in the rat.

Effect of Dietary Fructose on Fatty Acid Synthesis in Adipose Tissue and Liver of the Rat

Influence of periodicity of eating on the activity of adipose tissue and muscle glycogen synthesizing enzymes in the rat.

Joyce H. Wiley

Papers

Influence of dietary lipid on lipogenesis and on the activity of malic enzyme and citrate cleavage enzyme in liver of the growing chick.

Significance of insulin in the metabolic adaptation of rats to meal ingestion.

Metabolic consequences of dietary medium-chain triglycerides in the rat.

Effect of Dietary Fructose on Fatty Acid Synthesis in Adipose Tissue and Liver of the Rat

Influence of periodicity of eating on the activity of adipose tissue and muscle glycogen synthesizing enzymes in the rat.