J
Juan F. Ascaso
Researcher at University of Valencia
Publications - 233
Citations - 4656
Juan F. Ascaso is an academic researcher from University of Valencia. The author has contributed to research in topics: Insulin resistance & Diabetes mellitus. The author has an hindex of 27, co-authored 231 publications receiving 4123 citations. Previous affiliations of Juan F. Ascaso include Menéndez Pelayo International University & Carlos III Health Institute.
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Journal ArticleDOI
Evaluation of clinical diagnosis criteria of familial ligand defective apoB 100 and lipoprotein phenotype comparison between LDL receptor gene mutations affecting ligand-binding domain and the R3500Q mutation of the apoB gene in patients from a South European population.
Ismael Ejarque,José T. Real,Sergio Martínez-Hervás,F. Javier Chaves,Sebastian Blesa,Ana B. García-García,Enrique Millan,Juan F. Ascaso,Rafael Carmena +8 more
TL;DR: It is concluded that the FDB lipoprotein phenotype was significantly less severe than that observed in FH carriers of LDLR gene missense ligand-binding domain mutations and subjects with the R3500Q mutation in apoB gene.
Journal ArticleDOI
Prevalence of metabolic syndrome and cardiovascular disease in a hypertriglyceridemic population.
Juan F. Ascaso,Jesús Millán,Rocio Mateo-Gallego,Antonio Ruiz,Manuel Suárez-Tembra,Rosa M. Borrallo,Daniel Zambon,Pedro González-Santos,Miguel Peres-de-Juan,Emili Ros +9 more
TL;DR: Hypertriglyceridemia is associated to the metabolic syndrome and diabetes, as well as the risk of CVD, independently of the levels of triglyceride levels, and may be an important marker in the screening of these severe metabolic and vascular abnormalities.
Journal Article
Impact of obesity in primary hyperlipidemias.
TL;DR: It is shown that insulin resistance is an important component of the metabolic derangement in FCH subjects; high fasting plasma free fatty acids and triglycerides levels correlate to insulin resistance, thus linking this abnormality to lipid metabolism.
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Polymorphisms of the UCP2 gene are associated with body fat distribution and risk of abdominal obesity in Spanish population.
Sergio Martínez-Hervás,Maria L. Mansego,Griselda de Marco,Fernando Martinez,Monica Pineda Alonso,Sonsoles Morcillo,Gemma Rojo-Martínez,José T. Real,Juan F. Ascaso,Josep Redon,Juan Carlos Martín Escudero,Federico Soriguer,Felipe J. Chaves +12 more
TL;DR: In this article, the authors investigated the possible association of genetic variations of the gene codifying the UCP2 protein with obesity and fat distribution, and they found association with waist circumference.
Journal ArticleDOI
FABP4 plasma levels are increased in familial combined hyperlipidemia.
Anna Cabré,Iolanda Lázaro,Montserrat Cofán,Estíbaliz Jarauta,Núria Plana,A. L. García-Otín,Juan F. Ascaso,Juan F. Ascaso,Raimon Ferré,Fernando Civeira,Emilio Ros,Lluís Masana +11 more
TL;DR: A hyperlipidemic mechanism of FCHL different from similar metabolic conditions where fat mass is strongly related to FABP4 and hypertriglyceridemia is supported.