Immobilization of a physiologically active material while keeping the function of the physiologically active material on a high level, which is conducted by immobilizing the physiologically active material onto a carrier through an alkylene oxide chain The immobilized physiologically active material thus obtained is useful for separation and purification of useful materials

Immobilized physiologically active material

Polymeric structure involving a first polymer having a linear segment and a second polymer having a macrocyle which is threaded onto said linear segment to form a rotaxane complex. The rotaxane complex is capable of reversibly dissociating back into the individual polymers under the influence of an external factor, such as temperature and/or solvent exposure.

Reversible, mechanically interlocked polymeric networks which self-assemble

Reagent consisting essentially of a solid support made of a hydrophobic polymer on the surface of which are covalently fixed hydrophilic side chains of formula I in which Z is a nonhydroxylated hydrophilic organic spacer arm whose chain contains from 4 to 70 carbon atoms, Z' and Z" together denote =O, a group protecting the carbonyl group, or a group =YL in which Y denotes =N- or =@= and L denotes the residue of an amino ligand of diagrammatic formula L-NH2 or L=NH, or Z" denotes H and Z' denotes -NH-L, L being the residue of the said ligand; its preparation and its application especially to the detection of antigens in the field of medical diagnosis.

Solid-phase reagent for the covalent fixation of an aminated biological ligand, its preparation and use

Particules de polymere comportant, implantees a leur surface, des molecules d'un compose amphiphile constitue d'une sequence hydrophile oligomere terminee par un groupe ionogene ou reactif et d'une sequence hydrophobe emmelee avec les chaines macromoleculaires du polymere. polymer particles comprising, implanted at their surface, molecules of an amphiphilic compound consisting of a hydrophilic oligomer block terminated by an ion-forming or reactive group and a hydrophobic sequence entangled with the macromolecular chains of the polymer. Elles sont preparees par mise en contact du compose amphiphile avec un latex dudit polymere a une temperature comprise dans la zone de transition vitreuse dudit polymere, elimination du compose amphiphile non fixe et eventuellement separation des particules. They are prepared by contacting the amphiphilic compound with a latex of said polymer at a temperature within the glass transition zone of the polymer, removing the unbound amphiphilic compound and optionally separation of the particles. Lesdites particules ou leurs dispersions aqueuses peuvent etre utilisees en biologie. Said particles or their aqueous dispersions can be used in biology.

Polymer particles containing implanted in their surface amphiphilic molecules having ionic or reactive groups, process for preparing same and application in biology

Fiber or a foil comprises a polymer, preferably a polyamide or polyester, where the polymer exists as a macro cyclic ring molecule of cyclodextrin, cucurbituril and/or their derivatives, and as a rotaxan or pseudorotaxan An independent claim is included for the preparation of the fiber or the foil comprising at least partially linking the monomer units to the polymer with at least one macro-cyclic ring molecule

Fiber or foil, useful to prepare high temperature-resistant and/or tear-proof textiles, comprises polymer, preferably polyamide or polyester, as macro cyclic ring molecule of cyclodextrin or cucurbituril and as rotaxan or pseudorotaxan

To the surface of a polymer A, there is grafted a chemically different second component C which may be polymer, oligomer or monomer but is not the same as A, but which reacts with bi- or polyfunctional cpds. B already incorporated in A, ring formation occuring in the catenane or rotaxane manner, in which >=1 chains of polymer A may be included.

Juergen Gauger

Papers

Surface-modification of polymer films, fibres, etc. - by formation of caten-ane - or rotaxane-like bonds by a grafting reaction