J
Juliana Cristina Marcarini
Researcher at Universidade Estadual de Londrina
Publications - 15
Citations - 395
Juliana Cristina Marcarini is an academic researcher from Universidade Estadual de Londrina. The author has contributed to research in topics: Genotoxicity & Comet assay. The author has an hindex of 9, co-authored 15 publications receiving 339 citations. Previous affiliations of Juliana Cristina Marcarini include Sao Paulo State University.
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Journal ArticleDOI
The azo dyes Disperse Red 1 and Disperse Orange 1 increase the micronuclei frequencies in human lymphocytes and in HepG2 cells
Farah Maria Drumond Chequer,José Pedro Friedmann Angeli,Elisa Raquel Anastácio Ferraz,Marcela Stefanini Tsuboy,Juliana Cristina Marcarini,Mário Sérgio Mantovani,Danielle Palma de Oliveira +6 more
TL;DR: Evaluating the mutagenic activity of Disperse Red 1 and Disperse Orange 1 using the micronucleus (MN) assay in human lymphocytes and in HepG2 cells found that the number of MN induced by the lowest concentration of each dye was similar to that of the negative control.
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Investigation of cytotoxic, apoptosis-inducing, genotoxic and protective effects of the flavonoid rutin in HTC hepatic cells.
Juliana Cristina Marcarini,Marcela Stefanini Tsuboy,Rodrigo Cabral Luiz,Lúcia Regina Ribeiro,Clara Beatriz Hoffmann-Campo,Mário Ségio Mantovani +5 more
TL;DR: Rutin was tested against the pro-carcinogenic agent benzo(a)pyrene, at concentrations of 90, 270 and 810 μM, and was found to reduce induced DNA damage significantly, suggesting an important biological activity for this compound, which can contribute to human health through the diet.
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Chlorination treatment of aqueous samples reduces, but does not eliminate, the mutagenic effect of the azo dyes Disperse Red 1, Disperse Red 13 and Disperse Orange 1
Gisele Augusto Rodrigues de Oliveira,Elisa Raquel Anastácio Ferraz,Farah Maria Drumond Chequer,Marcella D. Grando,José Pedro Friedmann Angeli,Marcela Stefanini Tsuboy,Juliana Cristina Marcarini,Mário Sérgio Mantovani,Marly E. Osugi,Thiago Mescoloto Lizier,Maria Valnice Boldrin Zanoni,Danielle Palma de Oliveira +11 more
TL;DR: It was concluded that conventional chlorination should be used with caution for the treatment of aqueous samples contaminated with azo dyes, because chlorination of these dyes is not efficient in mineralizing them.
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Cytotoxic, biochemical and genotoxic effects of biodiesel produced by different routes on ZFL cell line
Dalita Gomes Silva Morais Cavalcante,Natara D.G. da Silva,Juliana Cristina Marcarini,Mário Sérgio Mantovani,Maria Aparecida Marin-Morales,Cláudia B.R. Martinez +5 more
TL;DR: Both Bd seem to be stressors for the cells, causing cytotoxic, biochemical and genetic alterations in ZFL cells, but the type and intensity of the changes found appear to be dependent on the biodiesel production route.
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Genistein at Maximal Physiologic Serum Levels Induces G0/G1 Arrest in MCF-7 and HB4a Cells, But Not Apoptosis
Marcela Stefanini Tsuboy,Juliana Cristina Marcarini,Alecsandra Oliveira de Souza,Natália Aparecida de Paula,Daniel Junqueira Dorta,Mário Sérgio Mantovani,Lúcia Regina Ribeiro +6 more
TL;DR: Investigation of cytotoxicity, induction of apoptosis, and changes in apoptosis-related genes of maximal physiological serum levels of the isoflavone genistein in MCF-7 tumoral cells and in HB4a non-tumoral cells found that Gen at physiologically relevant serum levels still exerts chemopreventive effects through the modulation of cell cycle.