J
Junqing Liu
Researcher at Zhejiang University
Publications - 4
Citations - 263
Junqing Liu is an academic researcher from Zhejiang University. The author has contributed to research in topics: DNA methylation & Nedaplatin. The author has an hindex of 3, co-authored 4 publications receiving 94 citations.
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Journal ArticleDOI
The Drug-Resistance Mechanisms of Five Platinum-Based Antitumor Agents.
TL;DR: This review summarizes the critical participators of platinum resistance mechanisms and highlights the most potential therapeutic targets or predicted markers to extend the clinical application of platinum-based antitumor agents largely.
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Research and development of drug delivery systems based on drug transporter and nano-formulation.
TL;DR: This review focuses on the application of novel nano-agents targeting transporters and the introduction of drug-transporter-based nano-formulations.
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The failure of DAC to induce OCT2 expression and its remission by hemoglobin-based nanocarriers under hypoxia in renal cell carcinoma
Lu Chen,Wang Zeyang,Qingwen Xu,Yuxi Liu,Le Chen,Suhang Guo,Hua Wang,Kui Zeng,Junqing Liu,Su Zeng,Lushan Yu +10 more
TL;DR: DAC was unable to upregulate OCT2 expression in hypoxic conditions because of the hypermethylation and low H3K4me3 modification in its promoter region, and hypoxia-mediated repression of ENT1 led to the inability of DAC toUpregulate the expression of OCT2 under hypoxIA.
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Metastatic colorectal cancer: Perspectives on long non-coding RNAs and promising therapeutics.
TL;DR: In this paper, the authors focus on current understanding of the modes of action of lncRNAs, and review their regulatory roles in metastatic colorectal cancer, and discuss correlated potential lncRNA-based therapeutics.