J
Jürgen A. Richt
Researcher at Kansas State University
Publications - 163
Citations - 5648
Jürgen A. Richt is an academic researcher from Kansas State University. The author has contributed to research in topics: Virus & Medicine. The author has an hindex of 41, co-authored 126 publications receiving 5120 citations. Previous affiliations of Jürgen A. Richt include United States Department of Agriculture & University of Texas MD Anderson Cancer Center.
Papers
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Book ChapterDOI
Swine influenza viruses a North American perspective.
Amy L. Vincent,Wenjun Ma,Wenjun Ma,Wenjun Ma,Kelly M. Lager,Bruce H. Janke,Jürgen A. Richt,Jürgen A. Richt +7 more
TL;DR: It is expected that the dynamic evolutionary changes of SIVs in North American pigs will continue, making currently available prophylactic approaches of limited use to control the spread and economic losses associated with this important swine pathogen critical.
Journal ArticleDOI
Mutations in the NS1 protein of swine influenza virus impair anti-interferon activity and confer attenuation in pigs.
Alicia Solórzano,Richard J. Webby,Kelly M. Lager,Bruce H. Janke,Adolfo García-Sastre,Jürgen A. Richt +5 more
TL;DR: The data suggest that the NS1 protein of SIV is a virulence factor, and NS1-mutated swine influenza viruses might have a great potential as live attenuated vaccine candidates against SIV infections of pigs.
Journal ArticleDOI
Identification of H2N3 influenza A viruses from swine in the United States.
Wenjun Ma,Amy L. Vincent,Marie Gramer,Christy B. Brockwell,Kelly M. Lager,Bruce H. Janke,Phillip C. Gauger,Devi P. Patnayak,Richard J. Webby,Jürgen A. Richt +9 more
TL;DR: The isolate and characterize genetically similar avian/swine virus reassortant H2N3 influenza A viruses isolated from diseased swine from two farms in the United States suggest that the H2n3 virus has undergone some adaptation to the mammalian host and that their spread should be very closely monitored.
Journal ArticleDOI
Vaccination of Pigs against Swine Influenza Viruses by Using an NS1-Truncated Modified Live-Virus Vaccine
Jürgen A. Richt,Porntippa Lekcharoensuk,Kelly M. Lager,Amy L. Vincent,Christina M. Loiacono,Bruce H. Janke,Wai-Hong Wu,Kyoung-Jin Yoon,Richard J. Webby,Alicia Solórzano,Adolfo García-Sastre +10 more
TL;DR: Vaccinated pigs were seronegative for NS1, indicating the potential use of the TX98 NS1▴126 modified live virus (MLV) as a vaccine to differentiate infected from vaccinated animals.
BookDOI
Wildlife and Emerging Zoonotic Diseases: The Biology, Circumstances and Consequences of Cross-Species Transmission
TL;DR: This book discusses the conceptualizing and Partitioning the Emergence process of Zoonotic Viruses from Wildlife to Humans, and the Surveillance and Response to Disease Emergence.