J
Jurij Dolenšek
Researcher at University of Maribor
Publications - 44
Citations - 1396
Jurij Dolenšek is an academic researcher from University of Maribor. The author has contributed to research in topics: Beta cell & Calcium imaging. The author has an hindex of 14, co-authored 36 publications receiving 954 citations.
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Journal ArticleDOI
Network science of biological systems at different scales: A review
Marko Gosak,Rene Markovič,Jurij Dolenšek,Marjan Slak Rupnik,Marko Marhl,Andraž Stožer,Matjaž Perc +6 more
TL;DR: This work presents research highlights ranging from determination of the molecular interaction network within a cell to studies of architectural and functional properties of brain networks and biological transportation networks, and focuses on synergies between network science and data analysis, which enable us to determine functional connectivity patterns in multicellular systems.
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Structural similarities and differences between the human and the mouse pancreas
TL;DR: The structure of the human and the mouse pancreas, together with the similarities and differences between them are reviewed in detail in the light of conceivable repercussions for basic research and clinical application.
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Functional Connectivity in Islets of Langerhans from Mouse Pancreas Tissue Slices
Andraž Stožer,Marko Gosak,Jurij Dolenšek,Matjaž Perc,Marko Marhl,Marjan Slak Rupnik,Dean Korošak +6 more
TL;DR: Focusing on the temporal evolution of the network under stimulation with glucose, it is shown that the dynamics are more correlated under stimulation than under non-stimulated conditions and that the highest overall correlation is observed in the activation and deactivation phases when cells are driven by the external stimulus.
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Glucose-Stimulated Calcium Dynamics in Islets of Langerhans in Acute Mouse Pancreas Tissue Slices
TL;DR: Stable fast calcium oscillations on a sustained plateau rather than slow oscillations as the predominant type of response in acute tissue slices are reproducibly shown and calcium waves are the mechanistic substrate for synchronization of oscillations.
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The triggering pathway to insulin secretion: Functional similarities and differences between the human and the mouse β cells and their translational relevance
TL;DR: This review follows the most central triggering pathway to insulin secretion from its very beginning when glucose enters the β cell to the calcium oscillations it produces to trigger fusion of insulin containing granules with the plasma membrane.