https://chemistry.mdma.ch/hiveboard/rhodium/pdf/archive/merbst/quinoline1999.pdf

Quinoline, quinazoline and acridone alkaloids

The chemistry of recently isolated naturally occurring quinazolinone alkaloids

Rutaecarpine is an indolopyridoquinazolinone alkaloid isolated from Evodiarutaecarpa and related herbs, which has shown a variety of intriguing biological propertiessuch as anti-thrombotic, anticancer, anti-inflammatory and analgesic, anti-obesity andthermoregulatory, vasorelaxing activity, as well as effects on the cardiovascular andendocrine systems. Recent progress in the studies on the isolation, synthesis, structureactivityrelationship studies, biological activities and metabolism of rutaecarpine arereviewed.

/pdf/progress-in-the-studies-on-rutaecarpine-1yhrfl6u0s.pdf

Jyh Her Yeh

Papers

The heartwood constituents of Tetradium glabrifolium

7-hydroxyrutaecarpine from tetradium glabrifolium and tetradium ruticarpum