K
K. L. Linseman
Publications - 2
Citations - 188
K. L. Linseman is an academic researcher. The author has contributed to research in topics: Lipid peroxidation & Trolox. The author has an hindex of 2, co-authored 2 publications receiving 187 citations.
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Journal Article
U-78517F: a potent inhibitor of lipid peroxidation with activity in experimental brain injury and ischemia.
Edward D. Hall,J M Braughler,P A Yonkers,S. L. Smith,K. L. Linseman,Eugene D. Means,H. M. Scherch,P. F. Von Voigtlander,Robert A. Lahti,E. J. Jacobsen +9 more
TL;DR: Both stereoisomers of the racemic U-78517F proved to be equally active antioxidants, and evidence of an in vivo antioxidant action was provided by the attenuation of iron-induced blood-brain barrier disruption in rats pretreated with U-77517F.
Journal Article
Nonsteroidal lazaroid U78517F in models of focal and global ischemia.
TL;DR: The results document the anti-ischemic efficacy of a novel and potent inhibitor of iron-catalyzed lipid peroxidation and further support a key role of oxygen radicals in postischemi brain damage.