K
Karen A. Homer
Researcher at King's College London
Publications - 28
Citations - 993
Karen A. Homer is an academic researcher from King's College London. The author has contributed to research in topics: Streptococcus oralis & Sialic acid. The author has an hindex of 17, co-authored 28 publications receiving 944 citations.
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Journal ArticleDOI
Analysis of Streptococcus mutans Proteins Modulated by Culture under Acidic Conditions
TL;DR: The identification of proteins differentially expressed following growth at low pH provides new information regarding the mechanisms of survival and has identified new target genes for mutagenesis studies to further assess their physiological significance.
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Effect of Acidic pH on Expression of Surface-Associated Proteins of Streptococcus oralis
TL;DR: This study has extended the range of streptococcal proteins known to be expressed at the cell surface by identifying the most abundant surface-associated proteins of S. oralis and investigating changes in protein expression when the organism was grown under acidic culture conditions.
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Two closely related ABC transporters in streptococcus mutans are involved in disaccharide and/or oligosaccharide uptake.
TL;DR: It is proposed that the ATPase domains of these ABC transporters can interact with either their own or the alternative transporter complex, and such unexpected interaction of ATPase subunits with distinct membrane components to form complete multiple ABCtransporters may be widespread in bacteria.
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Altered Protein Expression of Streptococcus oralis Cultured at Low pH Revealed by Two-Dimensional Gel Electrophoresis
TL;DR: Gen products that may be important in the survival and proliferation of nonmutans aciduric S. oralis under conditions of low pH that are likely to be encountered by this organism in vivo are identified for the first time.
Journal ArticleDOI
Plasma heat shock protein 60 and cardiovascular disease risk: the role of psychosocial, genetic, and biological factors.
Alireza Shamaei-Tousi,Andrew Steptoe,Katie O'Donnell,J. Palmen,Jeffrey W. Stephens,Steven J. Hurel,Michael Marmot,Karen A. Homer,Francesco D'Aiuto,Anthony R.M. Coates,Steve E. Humphries,Brian Henderson +11 more
TL;DR: The extended range of plasma Hsp60 concentrations in the general population is genuine and is likely to be related to genetic, biological, and psychosocial risk factors for coronary artery disease.