K
Karen Lise Welling
Researcher at Copenhagen University Hospital
Publications - 8
Citations - 367
Karen Lise Welling is an academic researcher from Copenhagen University Hospital. The author has contributed to research in topics: Fibrinolysis & Coagulopathy. The author has an hindex of 5, co-authored 6 publications receiving 311 citations.
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Journal ArticleDOI
Disseminated intravascular coagulation or acute coagulopathy of trauma shock early after trauma? An observational study
Pär I. Johansson,Anne Marie Sørensen,Anders Perner,Karen Lise Welling,Michael Wanscher,Claus Falck Larsen,Sisse R. Ostrowski +6 more
TL;DR: In non-ACoTS patients, apart from APTT/INR, higher ISS correlated with biomarkers of enhanced tissue, endothelial cell and glycocalyx damage, protein C activation, coagulation factor consumption, hyperfibrinolysis and inflammation, similar to that observed in patients with ACoTS.
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Trauma-Induced Coagulopathy: Standard Coagulation Tests, Biomarkers of Coagulopathy, and Endothelial Damage in Patients with Traumatic Brain Injury
Gustav Folmer Genét,Pär I. Johansson,Martin A. S. Meyer,Sacha Sølbeck,Anne Marie Sørensen,Claus Falck Larsen,Karen Lise Welling,Nis A. Windeløv,Lars S. Rasmussen,Sisse R. Ostrowski +9 more
TL;DR: Traditional coagulation tests, biomarkers of coagulopathy, and endothelial damage in trauma patients with and without TBI were investigated and no significant biomarker differences were found between isoTBI and non-TBI patients.
Journal ArticleDOI
High sCD40L levels early after trauma are associated with enhanced shock, sympathoadrenal activation, tissue and endothelial damage, coagulopathy and mortality
Pär I. Johansson,Anne Marie Sørensen,Anders Perner,Karen Lise Welling,Michael Wanscher,Claus Falck Larsen,Sisse R. Ostrowski +6 more
TL;DR: High early sCD40L levels in trauma patients reflect tissue injury, shock, coagulopathy and sympathoadrenal activation and predict mortality as s CD40L has pro‐inflammatory activity and activates the endothelium.
Journal ArticleDOI
Elderly trauma patients have high circulating noradrenaline levels but attenuated release of adrenaline, platelets, and leukocytes in response to increasing injury severity.
Pär I. Johansson,Anne Marie Sørensen,Anders Perner,Karen Lise Welling,Michael Wanscher,Claus Falck Larsen,Sisse R. Ostrowski +6 more
TL;DR: In trauma patients, the association between age and mortality was confirmed and older patients displayed a biomarker profile suggestive of enhanced release, activation, and consumption of the natural anticoagulants and hyperfibrinolysis.
Journal ArticleDOI
Update on acute endovascular and surgical stroke treatment.
Daniel Kondziella,M. Cortsen,Vagn Eskesen,Klaus Hansen,Markus Holtmannspötter,J. Højgaard,Trine Stavngaard,H. Søndergaard,A. Wagner,Karen Lise Welling +9 more
TL;DR: Using a case‐based approach, this article reviews recent achievements in advanced treatment options for patients with acute ischemic stroke, finding decompressive craniectomy is now a well‐established treatment option for malignant middle cerebral artery infarction and cerebellar stroke.