A system for calibrating a device for measuring materials concentration in the blood is disclosed. The system may include at least two sets of calibrating elements, each set may include a plurality of calibrating elements. Each of the calibrating elements in the sets may include, a first layer simulating a specific human skin characteristics; and a second layer consisting a specific concentration of one or more materials in the blood. For all calibrating elements in a set the first layer may be the same first layer simulating the same human skin characteristics such that each set of calibrating elements simulate different skin characteristics. Each calibrating element in a set of calibrating elements may include a different second layer consisting a different concentration of the one or more materials. The system may further include a controller.

Device, system and method for calibrating a non-invasive health monitoring device

FIELD: medicine.SUBSTANCE: clinical and laboratory criteria: gender, age - are determined. History data is determined: intake of new drugs, alcohol, newly diagnosed liver pathology, disease symptoms in the premenstrual period, emotional instability. The presence of tachycardia, arterial hypertension, dyskinesia of the gastrointestinal tract: constipation or diarrhea, nausea and vomiting, pain in the abdomen - are also determined. Presence of urine dark in daylight is identified. The presence of muscle weakness in the form of tetraparesis, paraparesis, hemiparesis is determined. The presence of a violation of urination and defecation control; violation of sensitivity are revealed as well, body temperature, appearance of hallucinations and delirium, epileptiform seizures are determined. The presence of dyspnea, facial nerve paresis, bulbar disorders is determined. The presence of leukocytosis of more than 12*10/l and ESR of more than 30 mm/h, bilirubinuria, erythrocyturia, excess reference values of uric acid, urea and hyponatremia are revealed as laboratory indicators. Clinical and laboratory criteria are scored in accordance with Table 1 contained in the description. The derived points are summed up. If the score is less than 5 - acute porphyria is unlikely, from 5 to 15 - porphyria is possible, more than 15 - acute porphyria is highly probable.EFFECT: method allows to effectively and quickly identify patients with acute porphyria due to comprehensive assessment of the most significant indicators.2 dwg, 3 tbl, 3 ex

Method for identification of patients with first attacks of acute porphyria

FIELD: medicine. ^ SUBSTANCE: invention contains body which consists of base and cover, made from fluoroplast, and device for imitation of optical properties of various types of live biological tissues. Device includes set of layer-by-layer placed elements which possess light-dispersing, fluorescent and light-absorbing optical properties. Layer-by-layer placed elements represent polymer optical films, whose spectral linear coefficients of absorption and dispersion correspond to spectral linear coefficients of light absorption by biological tissues with superficial and epidermal melanin, blood saturated with oxygen on 5-100%, spectral linear coefficient of light dispersion by collagen fibres and dense tissue structure without blood. Wavelengths of fluorescence of polymer optic films correspond to wavelengths of fluorescence of respiratory cell enzymes of biological tissue. ^ EFFECT: application of invention extends functional possibilities of device and ensures calibration and check-up of vast range of devices and apparatuses of non-invasive medical spectrophotometry. ^ 3 cl, 1 dwg, 1 tbl

Device for calibration of medical diagnostic spectrophotometric devices

FIELD: medicine, diagnostics. ^ SUBSTANCE: due to spectrophotometry on should study body biological material to detect the concentration of porphyrin in tissues of biological material and compare it values against the standard. As biological material one should apply that part of the tissue at patient's body where spectrophotometric investigation should be carried out in vivo. Moreover, One should affect this part with low-intensity laser radiation, wave length corresponds to one of the maximums of protoporphyrins' absorption range. One should determine the amplitude of fluorescence radiation of this part. As a standard for comparison one should take the amplitude of fluorescence of protoporphyrin IX that models the concentration of protoporphyrin in blood erythrocytes ranged 100-1500 mcg/l and more. At equality of amplitudes it is necessary to establish concentration of proptoporphyrin IX in blood erythrocytes of biological tissue under testing. Moreover, wave lengths corresponding to maximums of absorption range of protoporphyrins correspond to 337, 370, 405, 532, 632 nm. The innovation enables to considerably simplify the investigation of values that indirectly characterize lead concentration in tissues and, thus, total degree lead intoxication in patients with the risk of lead intoxication. ^ EFFECT: higher efficiency of diagnostics. ^ 1 cl, 1 ex

Karpov Vasilij Nikolaevich

Papers

Device for calibration of medical diagnostic spectrophotometric devices

Method for predicting body intoxication with lead