K
Katherine S. Young
Publications - 2
Citations - 127
Katherine S. Young is an academic researcher. The author has contributed to research in topics: Janus kinase & Internal medicine. The author has an hindex of 1, co-authored 1 publications receiving 122 citations.
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Azithromycin blocks neutrophil recruitment in Pseudomonas endobronchial infection
Wan C. Tsai,Michael L. Rodriguez,Katherine S. Young,Jane C. Deng,Victor J. Thannickal,Kazuhiro Tateda,Marc B. Hershenson,Theodore J. Standiford +7 more
TL;DR: It is indicated that the azithromycin treatment in vivo results in significant reduction in airway-specific inflammation, which occurs in part by inhibition of neutrophil recruitment to the lung through reduction in proinflammatory cytokine expression and inhibition ofNeutrophil migration via the extracellular signal-regulated kinase-1 and -2 signal transduction pathway.
Journal ArticleDOI
Pacritinib for myelofibrosis in adults with thrombocytopenia.
TL;DR: Pacritinib as discussed by the authors is a new oral kinase inhibitor specifically targeting Janus kinase 2 (JAK2), interleukin-1 receptor-associated kinase 1 (IRAK-1) and colony-stimulating factor 1 receptor (CSF-1R), and is indicated for the treatment of adults with moderate or high risk of primary or secondary myelofibrosis (postpolycythemia or post-primary thrombocytopenia) whose platelet count is less than 50 × 109/L.