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Kathleen Benfell

Researcher at Brigham and Women's Hospital

Publications -  12
Citations -  1374

Kathleen Benfell is an academic researcher from Brigham and Women's Hospital. The author has contributed to research in topics: Parenteral nutrition & Glutamine. The author has an hindex of 7, co-authored 12 publications receiving 1360 citations. Previous affiliations of Kathleen Benfell include Harvard University.

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Clinical and metabolic efficacy of glutamine-supplemented parenteral nutrition after bone marrow transplantation. A randomized, double-blind, controlled study.

TL;DR: Patients receiving glutamine-supplemented parenteral nutrition after bone marrow transplantation had improved nitrogen balance, a diminished incidence of clinical infection, lower rates of microbial colonization, and shortened hospital stay compared with patients receiving standard parenTERal nutrition.
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Safety and Metabolic Effects of L‐Glutamine Administration in Humans

TL;DR: Subsequent studies in patients receiving glutamine-enriched parenteral nutrition for several weeks confirmed the clinical safety of this approach in a catabolic patient population, and nitrogen retention appeared to be enhanced when glutamine was administered at a dose of 0.570 g/kg/day in a balanced nutritional solution.
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The Effects of Glutamine-Supplemented Parenteral Nutrition in Premature Infants

TL;DR: Glutamine appears to be safe for use in prematurely infants and seems to be conditionally essential in premature infants with extremely low birth weights.
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Anabolic Therapy with Growth Hormone Accelerates Protein Gain in Surgical Patients Requiring Nutritional Rehabilitation

TL;DR: GH therapy accelerated nutritional repletion and, therefore, may shorten the convalescence of the malnourished patient requiring a major surgical procedure.
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Glutamine-enriched intravenous feedings attenuate extracellular fluid expansion after a standard stress.

TL;DR: In this model of catabolic stress, fluid retention and expansion of the extracellular fluid compartment commonly observed after standard total parenteral nutrition can be attenuated by administering glutamine-supplemented intravenous feedings, possibly by protecting the host from microbial invasion and associated infection.