K
Kathleen M. Kantak
Researcher at Boston University
Publications - 101
Citations - 3111
Kathleen M. Kantak is an academic researcher from Boston University. The author has contributed to research in topics: Attention deficit hyperactivity disorder & Methylphenidate. The author has an hindex of 31, co-authored 98 publications receiving 2907 citations. Previous affiliations of Kathleen M. Kantak include Tufts University & University of Wisconsin-Madison.
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Journal ArticleDOI
Efficacy of a therapeutic cocaine vaccine in rodent models
Barbara S. Fox,Kathleen M. Kantak,Melissa A. Edwards,Kerry M. Black,Brenda K. Bollinger,Alison J. Botka,Tammy L. French,Terry L. Thompson,Victoria C. Schad,Julia L. Greenstein,Malcolm L. Gefter,Mark A. Exley,Philip A Swain,Thomas J. Briner +13 more
TL;DR: The feasibility of a therapeutic cocaine vaccine for the treatment of cocaine addiction is established, with decreased levels of cocaine measured in the brain of immunized mice only 30 seconds after intravenous administration of cocaine.
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Dissociable effects of lidocaine inactivation of the rostral and caudal basolateral amygdala on the maintenance and reinstatement of cocaine-seeking behavior in rats.
TL;DR: The rBLA and cBLA appear to selectively and dissociably regulate drug-seeking behavior under conditions of cocaine abstinence (cue-induced reinstatement) and repeated cocaine use (maintenance), respectively, and suggest that the basolateral amygdala may be more functionally heterogeneous than commonly thought for regulating drug- seeking behavior.
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Evaluation of anti-cocaine antibodies and a cocaine vaccine in a rat self-administration model.
Kathleen M. Kantak,Stephanie L. Collins,E. G. Lipman,Julian Bond,K. Giovanoni,Barbara S. Fox +5 more
TL;DR: Antagonism of cocaine self-administration across a range of doses is feasible after immunization with a cocaine vaccine as long as antibody levels are of a sufficient concentration.
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Context-dependent prefrontal cortex regulation of cocaine self-administration and reinstatement behaviors in rats.
TL;DR: The effects of lidocaine‐induced inactivation of two distinct PFC subregions, the prelimbic (PL) or dorsal agranular insular (AId) cortices, on drug‐seeking and drug‐taking behaviors under cocaine maintenance and reinstatement testing conditions in rats trained to self‐administer 1 mg/kg cocaine under a second‐order schedule of drug delivery are examined.
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Advancing the spontaneous hypertensive rat model of attention deficit/hyperactivity disorder.
Kathleen M. Kantak,Teghpal Singh,Kerry A. Kerstetter,Kimberly A. Dembro,Michael M. Mutebi,Roxann C. Harvey,Christian F. Deschepper,Linda P. Dwoskin +7 more
TL;DR: Evidence is provided that the spontaneous hypertensive rat (SHR) model of attention deficit/hyperactivity disorder (ADHD) is a valid model for studying ADHD-associated neurocognitive deficits and the current behavioral approach is appropriate to assess novel medications developed to target ADHD- associated neuroc cognitive deficits.