Ke Wang

TL;DR: Marginal resection, or gross-total resection when possible, should be performed in patients with primary chordomas to achieve better long-term survival, and both tumor location and bone invasion demonstrated clinical value.

TL;DR: Results suggested that β1-AABs exerted significant decreased ΔΨm, which may contribute to cardiac dysfunction, most likely by decreasing cardiac autophagy in vivo, and myocardial radionuclide imaging technology may be needed to assess the risk in developing cardiac dysfunction for the people who have β1 -AABs in their blood.

TL;DR: In vitro and in vivo overexpression of mitochondrial Omi/HtrA2 induces cardiac apoptosis and dysfunction, and strategies to directly inhibit Omi or its cytosolic translocation from mitochondria may protect against heart injury.

TL;DR: It is demonstrated that increased expression and leakage of Omi/HtrA2 enhanced MI/R injury in aging hearts via degrading XIAP and promoting myocardial apoptosis.

TL;DR: The nomogram appears useful for risk stratification of tumor progression in primary cases, and it will be necessary to identify the rapid‐growth histopathological subtype as an independent predictor of rapid progression.