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Ke Wei

Researcher at Nanjing Medical University

Publications -  22
Citations -  1341

Ke Wei is an academic researcher from Nanjing Medical University. The author has contributed to research in topics: microRNA & Lung cancer. The author has an hindex of 11, co-authored 17 publications receiving 602 citations.

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Journal ArticleDOI

Role of hypoxia in cancer therapy by regulating the tumor microenvironment

TL;DR: The role of Hypoxia in cancer therapy by regulating the tumor microenvironment (TME) is summarized and the potential of hypoxia-targeted therapy is highlighted to overcome hypoxian-associated resistance in cancer treatment.
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MicroRNA-1258 suppresses tumour progression via GRB2/Ras/Erk pathway in non-small-cell lung cancer.

TL;DR: Although miR‐1258 plays a vital role in suppressing metastasis in breast cancer and gastric cancer, the specific biological function of miR-1258 in non‐small‐cell lung cancer remains unclear.
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Long Noncoding RNA FAL1 Promotes Cell Proliferation, Invasion and Epithelial-Mesenchymal Transition Through the PTEN/AKT Signaling Axis in Non-Small Cell Lung Cancer.

TL;DR: FAL1 was significantly overexpressed in NSCLC compared with adjacent normal tissues, and a high level of FAL1 correlated with poor histological grade, increased lymph node metastasis and advanced TNM stage, which could lead to lncRNA-related diagnostics and therapeutics inNSCLC.
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MiR-106b-5p Promotes Proliferation and Inhibits Apoptosis by Regulating BTG3 in Non-Small Cell Lung Cancer

TL;DR: It is revealed for the first time that miR-106b-5p plays a tumorigenesis role in NSCLC progression by down-regulating BTG3 expression, which may lead to a novel insight to the potential biomarker and novel therapeutic strategies for NSCLc patients.
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MicroRNA-124 Functions as a Tumor Suppressor by Regulating CDH2 and Epithelial-Mesenchymal Transition in Non-Small Cell Lung Cancer

TL;DR: The findings present the first evidence that miR-124 could suppress the expression of CDH2 and regulate EMT, which might lead to a potential therapeutic strategy focusing on mi R-124 andCDH2 for human lung cancer.