K
Kevin M. Creehan
Researcher at University of California, San Diego
Publications - 44
Citations - 1347
Kevin M. Creehan is an academic researcher from University of California, San Diego. The author has contributed to research in topics: Inhalation & Opioid. The author has an hindex of 18, co-authored 42 publications receiving 1177 citations. Previous affiliations of Kevin M. Creehan include Scripps Research Institute & University of California, Berkeley.
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Journal ArticleDOI
The novel recreational drug 3,4-methylenedioxypyrovalerone (MDPV) is a potent psychomotor stimulant: self-administration and locomotor activity in rats
TL;DR: MDPV poses a substantial threat for compulsive use that is potentially greater than that for METH, and stereotypy was associated with relatively high self-administered cumulative doses of MDPV as well as with non-contingent M DPV administration wherein the intensity and duration of stereotypy increased as MDPVs dose increased.
Journal ArticleDOI
Mephedrone (4-methylmethcathinone) supports intravenous self-administration in Sprague-Dawley and Wistar rats.
Shawn M. Aarde,Deepshikha Angrish,Deborah Barlow,M. Jerry Wright,Sophia A. Vandewater,Kevin M. Creehan,Karen L. Houseknecht,Tobin J. Dickerson,Michael A. Taffe +8 more
TL;DR: Evidence is provided of stimulant‐typical abuse liability for 4‐MMC in the traditional pre‐clinical self‐administration model and the number of responses and/or the total amount of drug self-administered varied as a function of dose.
Journal ArticleDOI
Effect of ambient temperature on the thermoregulatory and locomotor stimulant effects of 4-methylmethcathinone in Wistar and Sprague-Dawley rats.
M. Jerry Wright,Deepshikha Angrish,Shawn M. Aarde,Deborah Barlow,Matthew W. Buczynski,Kevin M. Creehan,Sophia A. Vandewater,Loren H. Parsons,Karen L. Houseknecht,Tobin J. Dickerson,Michael A. Taffe +10 more
TL;DR: Results show that the cathinone analog 4-MMC exhibits thermoregulatory and locomotor properties that are distinct from those established for methamphetamine or MDMA in prior work, despite recent evidence of neuropharmacological similarity with MDMA.
Journal ArticleDOI
Changes in ambient temperature differentially alter the thermoregulatory, cardiac and locomotor stimulant effects of 4-methylmethcathinone (mephedrone)☆
Michelle L. Miller,Kevin M. Creehan,Deepshikha Angrish,Deborah Barlow,Karen L. Houseknecht,Tobin J. Dickerson,Michael A. Taffe +6 more
TL;DR: Results show that the cathinone analog 4-MMC exhibits in vivo thermoregulatory properties that are distinct from those produced by MDMA.
Journal ArticleDOI
In vivo potency and efficacy of the novel cathinone α-pyrrolidinopentiophenone and 3,4-methylenedioxypyrovalerone: self-administration and locomotor stimulation in male rats
TL;DR: The potency and efficacy of MDPV and alpha-PVP were very similar across multiple assays, predicting that the abuse liability of alpha-pyrrolidinopentiophenone will be significant and similar to that of M DPV.