Kira Kondratyeva

TL;DR: The data highlight the complex evolution of MDR and XDR K. pneumoniae, involving transfer and spread of ARGs, and epidemic plasmids in highly disseminating successful clones, and a need for future genomic and translational studies to decipher specific targets in HiR clones to design targeted prevention and treatment.

TL;DR: This study offers a comprehensive way to decipher plasmid-bacterium associations and demonstrates that the CTX-M-encoding ST131 Group1 and Group2 plasmids are clade-restricted and presumably less transmissible, potentially contributing to ST131 clonal superiority.

TL;DR: It is found that shedding rates and bacterial species diversity increased significantly during hospitalization, both in mares and foals, and further investigation and surveillance of ESBL-E in neonatal foals is suggested in order to reduce resistance rates and infections.

TL;DR: This study demonstrates ST131 superiority that may explain its improved gut‐colonization and dissemination capabilities within the host, and group analysis showed that ST131 surpassed non‐ST131 lineages in all three physiological properties.

TL;DR: In this paper, the authors performed a comprehensive genomic analysis (Illumina and MinION) and virulence studies using Caenorhabditis elegans nematodes to evaluate KpnU95, a blaCTX-M-15-producing CA-UTI K. pneumoniae strain.