K
Kirk M. Ririe
Researcher at University of Utah
Publications - 33
Citations - 1559
Kirk M. Ririe is an academic researcher from University of Utah. The author has contributed to research in topics: Nucleic acid & DNA. The author has an hindex of 12, co-authored 33 publications receiving 1484 citations. Previous affiliations of Kirk M. Ririe include BioMérieux.
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Patent
Monitoring amplification of DNA during PCR
TL;DR: In this article, methods for quantitating amplified DNA and determining its purity are carried out by analysis of melting and reannealing curves, achieved with rapid thermal cycling and use of double stranded DNA dyes or specific hybridization probes.
Journal ArticleDOI
FilmArray, an automated nested multiplex PCR system for multi-pathogen detection: development and application to respiratory tract infection.
Mark A. Poritz,Anne J. Blaschke,Carrie L. Byington,Lindsay Meyers,Kody Nilsson,David Jones,Thatcher Stephanie Anne,Thomas Charles Robbins,Beth Lingenfelter,Elizabeth A. Amiott,Amy Herbener,Judy A. Daly,Steven F. Dobrowolski,David H.-F. Teng,Kirk M. Ririe +14 more
TL;DR: An integrated diagnostic platform, the FilmArray, which fully automates the detection and identification of multiple organisms from a single sample in about one hour, and it is demonstrated that automated identification of pathogens from their corresponding target amplicon can be accomplished by analysis of the DNA melting curve of the amplicon.
Patent
System and methods for monitoring for DNA amplification by fluorescence
TL;DR: In this paper, a thermal cycling method and device is described, which comprises a sample chamber whose temperature can be rapidly and accurately modulated over a range of temperatures needed to carry out a number of biological procedures such as the DNA polymerase chain reaction.
Journal ArticleDOI
Rapid identification of pathogens from positive blood cultures by multiplex polymerase chain reaction using the FilmArray system
Anne J. Blaschke,Caroline Heyrend,Carrie L. Byington,Mark A. Fisher,Elizabeth Barker,Nicholas F. Garrone,Thatcher Stephanie Anne,Andrew T. Pavia,Trenda Barney,Garrison Alger,Judy A. Daly,Judy A. Daly,Kirk M. Ririe,Irene Ota,Mark A. Poritz +14 more
TL;DR: The FilmArray® (FA) Blood Culture panel is an accurate method for the rapid identification of pathogens and resistance genes from blood culture and compared to conventional culture and susceptibility testing on 102 archived blood cultures from adults and children with bacteremia.
Patent
Self-contained biological analysis
Kirk M. Ririe,Michael R. Newswander,Randy P. Rasmussen,Mark A. Poritz,Stewart Benjamin Smith,David Jones,Gary Clark Kessler +6 more
TL;DR: In this paper, the authors present devices, containers, and methods for performing biological analysis in a closed environment, including nucleic acid amplification and detection and immuno-PCR.